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Abgenix Reports First Quarter 2001 Results.


Business Editors/Health & Medical Writers

FREMONT Fremont (frē`mŏnt).

1 City (1990 pop. 173,339), Alameda co., W Calif., on San Francisco Bay; inc. 1956. Long an agricultural center, with champagne vineyards founded (1870) by Leland Stanford, it still ships fruits and vegetables.
, Calif.--(BW HealthWire)--April 24, 2001

Abgenix, Inc. (Nasdaq:ABGX) today reported a net loss of $7.6 million or $0.09 per share for the quarter ended March 31, 2001, compared to a net loss of $3.4 million or $0.05 per share for the quarter ended March 31, 2000. Contract revenues for the current quarter increased to $4.2 million from $2.0 million for the same quarter in 2000. Including interest income, total revenues for the current quarter increased to $14.5 million from $6.3 million for the same period in 2000.

Abgenix ended the first quarter with approximately ap·prox·i·mate  
adj.
1. Almost exact or correct: the approximate time of the accident.

2.
 $631.6 million in cash, cash equivalents and short-term Short-term

Any investments with a maturity of one year or less.


short-term

1. Of or relating to a gain or loss on the value of an asset that has been held less than a specified period of time.
 investments. In addition, Abgenix holds long-term Long-term

Three or more years. In the context of accounting, more than 1 year.


long-term

1. Of or relating to a gain or loss in the value of a security that has been held over a specific length of time. Compare short-term.
 investments, primarily equity in corporate partners, totaling $64.0 million.

First quarter company highlights included:
-- Presenting the Phase IIa clinical trial results of ABX-IL8 at the American
Academy of Dermatology meeting, showing that ABX-IL8 is associated with
statistically significant improvement in plaque psoriasis and has an excellent
safety profile,

-- Announcing preclinical results at the American Association for Cancer
Research meeting of ABX-IL8 showing anti-angiogenic and anti-tumor activity in
melanoma cells,

-- Initiating a Phase IIb clinical trial of ABX-IL8 in psoriasis,

-- Entering a manufacturing supply agreement with Lonza Biologics for the
exclusive use of a dedicated cell culture production suite at their facility in
Slough, England,

-- Entering an agreement to license Celltech the rights to use our SLAM
(Selected Lymphocyte Antibody Method) technology, the high throughput antibody
selection technology we obtained from the acquisition of ImmGenics,

-- Expanding our existing XenoMouse license agreements with Pfizer, Amgen and
Chiron,

-- Entering XenoMouse(TM)technology collaborations with Diabetogen, and with a
joint venture of Progenics and Cytogen,

-- Entering a second collaboration with Lexicon Genetics to validate potential
drug targets for our discovery and development of therapeutic human antibodies,


-- Entering a collaboration with Dyax to develop a new technology that will
combine our XenoMouse transgenic mouse antibody generating technology with
Dyax's phage display technology to create libraries of high affinity, fully
human antibody sequences,

-- Receiving a fourth U.S. patent grant relating to XenoMouse technology, and

-- Announcing the promotion of Ray Withy, Ph.D. to president and chief
operating officer, and the addition of Susan Thorner as vice president, general
counsel and secretary.


Abgenix is a biopharmaceutical company focused on the development and commercialization of fully human monoclonal antibody therapies Monoclonal antibody therapy is the use of monoclonal antibodies (or Mab) to specifically target cells. The main objective is stimulating the patient's immune system to attack the malignant tumor cells and the prevention of tumor growth by blocking specific cell receptors.  for a variety of diseases. The company's antibody antibody, protein produced by the immune system (see immunity) in response to the presence in the body of antigens: foreign proteins or polysaccharides such as bacteria, bacterial toxins, viruses, or other cells or proteins.  technology platform, which includes XenoMouse(TM) technology, enables the rapid generation and selection of high affinity The relationship that a person has to the blood relatives of a spouse by virtue of the marriage.

The doctrine of affinity developed from a Maxim of Canon Law that a Husband and Wife were made one by their marriage. There are three types of affinity.
, fully human antibody product candidates to essentially any disease target appropriate for antibody therapy antibody therapy Clinical immunology Any therapeutic intervention in which a monoclonal or other concentrated antibody is used to manage a condition–eg, cancer or severe infection . Abgenix leverages its leadership position in human antibody technology by building a large and diversified diversified (di·verˑ·s  product portfolio through the establishment of licensing arrangements with multiple pharmaceutical, biotechnology biotechnology, the use of biological processes, as through the exploitation and manipulation of living organisms or biological systems, in the development or manufacture of a product or in the technological solution to a problem.  and genomics ge·no·mics
n.
The study of all of the nucleotide sequences, including structural genes, regulatory sequences, and noncoding DNA segments, in the chromosomes of an organism.
 companies and through the development of its own internal proprietary products. For more information on Abgenix, visit the company's website at www.abgenix.com.

Statements made in this press release about Abgenix's XenoMouse technology, product development activities and collaborative col·lab·o·rate  
intr.v. col·lab·o·rat·ed, col·lab·o·rat·ing, col·lab·o·rates
1. To work together, especially in a joint intellectual effort.

2.
 arrangements other than statements of historical fact, are forward looking statements and are subject to a number of uncertainties that could cause actual results to differ materially from the statements made, including risks associated with the success of clinical trials, the progress of research and product development programs, the regulatory reg·u·late  
tr.v. reg·u·lat·ed, reg·u·lat·ing, reg·u·lates
1. To control or direct according to rule, principle, or law.

2.
 approval process, competitive products, future capital requirements Capital requirements

Financing required for the operation of a business, composed of long-term and working capital plus fixed assets.
 and the extent and breadth Breadth

The percentage of assets or stocks advancing relative to those unchanged or declining. Also the number of independent forecasts available per year. A stock picker forecasting returns to 100 stocks every quarter exhibits a breadth of 400, assuming each forecast is
 of Abgenix's patent portfolio. Please see Abgenix's public filings with the Securities and Exchange Commission for information about risks that may affect Abgenix.


SELECTED UNAUDITED FINANCIAL INFORMATION

CONSOLIDATED STATEMENT OF
OPERATIONS DATA                                   Three Months Ended
(in thousands except per share data)                   March 31,
                                               ----------------------
                                                  2001           2000

Revenues:
  Contract revenues                           $  4,176       $  1,965
  Interest income                               10,306          4,341
                                               -------        -------
    Total revenues                              14,482          6,306

Costs and Expenses:
  Research and development                      16,760          7,214
  General and administrative                     3,065          1,584
  Amortization of intangible assets              2,046            777
  Interest expense                                 255            114
                                               -------        -------
    Total costs and expenses                    22,126          9,689

Net loss                                      $ (7,644)      $ (3,383)
                                               =======        =======

Basic and diluted net loss per share          $  (0.09)      $  (0.05)
                                               =======        =======
Shares used in computing basic and diluted
    net loss per share                          85,661         74,772
                                               =======        =======



CONSOLIDATED BALANCE SHEET DATA               March 31,   December 31,
(in thousands)                                    2001           2000
                                               ----------------------
Cash, cash equivalents
  and marketable securities                   $631,578       $692,883
Other current assets                            21,613         25,155
                                               -------        -------
    Total current assets                       653,191        718,038
Property and equipment, net                     25,975         18,374
Long-term investment                            64,084         79,181
Intangible assets, net                         115,950        117,997
Deposits & other assets                         6,468           3,210
                                               -------        -------
Total assets                                  $865,668       $936,800
                                               =======        =======
Deferred revenue                              $  5,554       $  6,978
Other current liabilities                        9,617         14,151
Acquisition liabilities                         31,660         75,429
                                               -------        -------
Total current liabilities                       46,831         96,558
Deferred rent                                      722            567
Stockholders' equity                           818,115        839,675
                                               -------        -------
Total liabilities and stockholders' equity    $865,668       $936,800
                                               =======        =======
COPYRIGHT 2001 Business Wire
No portion of this article can be reproduced without the express written permission from the copyright holder.
Copyright 2001, Gale Group. All rights reserved. Gale Group is a Thomson Corporation Company.

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Publication:Business Wire
Geographic Code:1USA
Date:Apr 24, 2001
Words:814
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