Aastrom Biosciences announces first trial of Tissue Repair Cells for regeneration of vascular tissue cells in diabetics.Aastrom Biosciences, Inc., Ann Arbor, MI, announced that the first clinical trial utilizing the company's proprietary Tissue Repair Cells (TRCs) to treat limb ischemia in diabetic patients has been initiated at the Diabetes Center at the Heart and Diabetes Center North Rhine-Westphalia (Diabetes Center) located in Bad Oeynhausen, Germany. Aastrom says initiation of the trial followed the Diabetes Center's receipt of the licenses and the Investigational Medicinal Product medicinal product,
n a substance administered to humans or animals through injection, application, oral ingestion, inhalation, and so forth, whose purpose is to ultimately restore health or eliminate disease in an individual. Dossier (IMPD IMPD Indianapolis Metropolitan Police Department (Indianapolis, Indiana)
IMPD Investigational Medicinal Product Dossier
IMPD Inosine Monophosphate Dehydrogenase
IMPD Institute for Multi-Party Democracy ) necessary to manufacture and use cells for clinical trials in compliance with the new European Union directives The following is an incomplete thematic list of European Union directives: Anti-discrimination measures
The aim of the study is to evaluate the safety and ability of Aastrom's bone marrow-derived TRCs to regenerate functioning blood vessels in the legs of diabetic patients with limb ischemia. The company says it is intended that the patients may experience relief from clinical problems that are related to a loss of blood circulation, such as: deep "bed-sore type" ulcerated Ulcerated
Damaged so that the surface tissue is lost and/or necrotic (dead).
Mentioned in: Adenoid Hyperplasia wounds of the feet, pain, immobility, and infection.
Over the 12 months following treatment, the trial will evaluate whether the TRC TRC
(in South Africa) Truth and Reconciliation Commission: a commission which encourages people who committed human rights abuses or acts of terror during the apartheid era to reveal the truth about their crimes in return for immunity from prosecution treatment results in improved or complete healing of ulcers, as well as whether amputation amputation (ăm'pyətā`shən), removal of all or part of a limb or other body part. Although amputation has been practiced for centuries, the development of sophisticated techniques for treatment and prevention of infection has greatly can be avoided or delayed. The trial will also monitor the time to relapse if complete healing is not attended, and whether the prognosis for patient survival improves, compared to standard of care controls.