AVICENA FILES COMPOSITION OF MATTER PATENT APPLICATION.Avicena Group, Inc. (BULLETIN BOARD: AVGOE), Palo Alto, Calif., a late stage biotechnology company focused on commercializing its proprietary cellular energy modulation technology, has filed a composition of matter patent application with the United States Patent and Trademark Office The United States Patent and Trademark Office (PTO or USPTO) is an agency in the United States Department of Commerce that provides patent protection to inventors and businesses for their inventions, and trademark registration for product and intellectual property to cover potential treatments for Parkinson's disease, a progressive neurodegenerative disease.
This composition of matter patent broadly covers pharmaceutical formulations based on creatine creatine /cre·a·tine/ (kre´ah-tin) an amino acid occurring in vertebrate tissues, particularly in muscle; phosphorylated creatine is an important storage form of high-energy phosphate. derivatives alone or in combination with an anti-inflammatory compound for the treatment of Parkinson's. The company believes that this patent will further strengthen its intellectual property portfolio in Parkinson's, building upon existing use patents previously issued to Avicena with claims in neurology (US Patents 6,196,115 B1 and 6,706,764 B2). Specifically, this patent will provide additional IP protection for its current Parkinson's disease drug candidate, PD-02, and future generation drug candidates formulated to treat Parkinson's.
"This patent application is indicative of our efforts to create shareholder value by building our IP estate to provide additional protection for our cellular energy franchise and our Parkinson's disease drug candidates", stated Belinda Tsao-Nivaggioli, Ph.D., CEO (1) (Chief Executive Officer) The highest individual in command of an organization. Typically the president of the company, the CEO reports to the Chairman of the Board. of Avicena. "As previously announced, the National Institutes of Health (NIH "Not invented here." See digispeak.
NIH - The United States National Institutes of Health. ) initiated a Phase III trial evaluating our PD-02 compound to verify its ability to slow the progression of Parkinson's disease. As we enter later stage clinical trials and approach potential marketing approvals and commercialization, the strength of our IP becomes increasingly important."
PD-02 is a patented, proprietary therapeutic that has demonstrated the potential to improve neurological function. In clinical studies, PD-02 demonstrated significant improvements in UPDRS UPDRS Unified Parkinson Disease Rating Scale (Unified Parkinson's Disease Rating Scale Unified Parkinson's Disease Rating Scale Neurology A measure of severity of Parkinson's disease, based on a scale from 0 to 160 total scale and 0 to 44 motor section. See Parkinson's disease. ). Preclinical studies of PD-02 have showed significant neuroprotective properties including protection of the dopaminergic dopaminergic /do·pa·min·er·gic/ (do?pah-men-er´jik) activated or transmitted by dopamine; pertaining to tissues or organs affected by dopamine.
adj. cells that are affected in Parkinson's disease.
About Parkinson's Disease
Parkinson's disease is a progressive, neurodegenerative brain disorder that occurs when the neurons within the brain that are responsible for producing the chemical dopamine dopamine (dōp`əmēn), one of the intermediate substances in the biosynthesis of epinephrine and norepinephrine. See catecholamine.
One of the catecholamines, widely distributed in the central nervous system. die. Primary symptoms of the disease include involuntary shaking of the arms or legs (tremors), difficulty with balance, slowness of movement, and stiffness.
According to the Parkinson's Disease Foundation, roughly 1.5 million Americans suffer from Parkinson's disease, making it the second most common neurodegenerative disease after Alzheimer's disease. Approximately 60,000 new cases are diagnosed each year in the United States. There presently is no known cure for Parkinson's disease.
Avicena Group, Inc. is a late stage biotechnology company focused on developing products based on its proprietary understanding of the regulation of cellular energy processes. The company's core technologies, supported by a robust IP portfolio, have broad applications in both pharmaceuticals and dermaceuticals. Avicena's pharmaceutical program centers on rare neurological disorders (orphan diseases). The company is currently analyzing data from its Phase IIb/III trial in ALS Als (äls), Ger. Alsen, island, 121 sq mi (313 sq km), Sønderjylland co., S Denmark, in the Lille Bælt, separated from the mainland by the narrow Alensund. (Amyotrophic Lateral Sclerosis amyotrophic lateral sclerosis (ALS) (ā'mīətrōf`ik, sklĭrō`sĭs) or motor neuron disease, , or Lou Gehrig's disease Lou Geh·rig's disease
See amyotrophic lateral sclerosis. ). Near term, Avicena intends to initiate a Phase III trial in Huntington's disease to accompany the ongoing Phase III trial in Parkinson's disease of its lead drug candidate, PD-02, and funded and managed by NIH/NINDS. Avicena's science is well established and its products are safe and well tolerated. Unlike traditional biotechnology companies, Avicena's clinical programs are largely funded by government and non-profit organizations. Avicena presently derives revenue from the sale of proprietary ingredients to skin care manufacturers.
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