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ARIAD Reports Fourth Quarter and Full Year 1998 Financial Results.


CAMBRIDGE, Mass.--(BUSINESS WIRE)--March 9, 1999--ARIAD Pharmaceuticals, Inc. (Nasdaq:ARIA) today reported total revenues of $2.6 million for the fourth quarter of 1998, a decrease of $385,000 from the $3.0 million reported for the fourth quarter of 1997. The Company reported a net loss of $7.0 million or $.32 per share for the fourth quarter of 1998, up $1.9 million from the net loss of $ 5.1 million or $.27 per share reported for the fourth quarter of 1997.

For the full year 1998, ARIAD ARIAD Allison Research Index of Art and Design  reported revenues of $13.1 million, a 20% increase over the $11.0 million reported for the year ended December 31, 1997. The Company incurred a net loss of $26.2 million or $1.25 per share for the year ended December 31, 1998, up $13.6 million from the net loss of $12.6 million or $.66 per share reported for the prior year.

The reduction in revenue for the fourth quarter was due primarily to a $259,000 reduction in interest income. Research revenue was substantially unchanged. The 20% increase in total revenue for the year was due primarily to a 31% increase in research revenue resulting from increased services provided to the Hoechst-ARIAD Genomics Center (the "Genomics Center"), a 50/50 joint venture between ARIAD and Hoechst Marion Roussel, Inc. ("Hoechst Marion Roussel").

Research and development expenses for the fourth quarter increased to $8.4 million from $7.1 million reported for the fourth quarter of 1997 and for the full year increased from $20.3 million to $35.5 million. These increases are due to the expanded research services provided to the Genomics Center and increased drug development costs for ARIAD's graft-versus-host disease graft-versus-host disease
n.
A type of incompatibility reaction of transplanted cells against host tissues that possess an antigen not possessed by the donor. Also called graft-versus-host reaction.
 ("GvHD") product based on ARIAD's Regulated Gene Expression Technology ("ARGENT ar·gent  
n.
1. Heraldry The metal silver, represented by the color white.

2. Archaic Silver or something resembling it.
(tm)"). These costs include manufacturing, process development and other preclinical preclinical /pre·clin·i·cal/ (-klin´i-k'l) before a disease becomes clinically recognizable.

pre·clin·i·cal
adj.
1.
 development activities in preparation for clinical trials of AP 1903, which commenced in December 1998. AP 1903 is a proprietary small-molecule drug developed to treat GvHD, a complication complication /com·pli·ca·tion/ (kom?pli-ka´shun)
1. disease(s) concurrent with another disease.

2. occurrence of several diseases in the same patient.


com·pli·ca·tion
n.
 experienced by certain patients undergoing allogeneic allogeneic /al·lo·ge·ne·ic/ (-je-ne´ik)
1. having cell types that are antigenically distinct.

2. in transplantation biology, denoting individuals (or tissues) that are of the same species but antigenically
 bone marrow transplantation Bone Marrow Transplantation Definition

The bone marrow—the sponge-like tissue found in the center of certain bones—contains stem cells that are the precursors of white blood cells, red blood cells, and platelets.
.

At December 31, 1998, the Company reported cash and marketable securities Marketable Securities

Very liquid securities that can be converted into cash quickly at a reasonable price.

Notes:
Marketable securities are very liquid as they tend to have maturities less than one year, and the rate at which these securities can be bought or sold has
 of $14.2 million. Subsequently, on January 5, 1999, the Company completed the sale of 478,120 shares of its Series B Preferred Stock Stock shares that have preferential rights to dividends or to amounts distributable on liquidation, or to both, ahead of common shareholders.

Preferred stock is given preference over common stock. Holders of preferred stock receive dividends at a fixed annual rate.
 to Hoechst Marion Roussel and received proceeds of $5,747,000. In addition, on February 23, 1999, the Company received a $2,000,000 milestone payment from Hoechst Marion Roussel from its 1995 bone disease collaboration.

"We are pleased with the progress made at ARIAD in the fourth quarter," said Harvey J. Berger, M.D., chairman and chief executive officer at ARIAD. "During the quarter, we announced the first ARIAD product to enter human clinical trials. In addition, we strengthened our intellectual property base with the award of four patents, as well as the publication in Science of key ARIAD technology. We also were able to improve our cash position with the issuance of $5 million of Series C Convertible Preferred Stock Convertible Preferred Stock

Preferred stock that includes an option for the holder to convert the preferred shares into a fixed number of common shares, usually anytime after a predetermined date. Also known as "convertible preferred shares".
, and subsequently, in January with the issue of $5.7 million of Series B Preferred Stock and the award of a $2 million milestone payment from Hoechst Marion Roussel."

ARIAD Pharmaceuticals (www.ariad.com) is a leader in the discovery and development of orally administered therapeutics therapeutics

Treatment and care to combat disease or alleviate pain or injury. Its tools include drugs, surgery, radiation therapy, mechanical devices, diet, and psychiatry.
 based on signal transduction Signal transduction

The transmission of molecular signals from a cell's exterior to its interior. Molecular signals are transmitted between cells by the secretion of hormones and other chemical factors, which are then picked up by different cells.
 technology. ARIAD is developing diverse products in multiple businesses, including signal transduction inhibitors, gene and cell therapy (based on ARGENT(tm)) and functional genomics Noun 1. functional genomics - the branch of genomics that determines the biological function of the genes and their products
genomics - the branch of genetics that studies organisms in terms of their genomes (their full DNA sequences)
. ARIAD recently announced the commencement of Phase 1 human clinical trials on its small-molecule drug (AP1903) to treat GvHD using ARGENT(tm) in patients undergoing allogeneic bone marrow transplants bone marrow transplant: see bone marrow. .

Some of the matters discussed in this news release are forward-looking statements forward-looking statement

A projected financial statement based on management expectations. A forward-looking statement involves risks with regard to the accuracy of assumptions underlying the projections.
 that involve risks and uncertainties, including, but not limited to, risks and uncertainties regarding the success of the Company's operations, as well as risks and uncertainties relating to relating to relate prepconcernant

relating to relate prepbezüglich +gen, mit Bezug auf +acc 
 economic conditions, markets, products, competition, intellectual property, services and prices, key employees, future capital needs, dependence on our collaborators and other factors discussed under the heading "Cautionary Statement Regarding Forward-Looking Statements" in ARIAD's Annual Report on Form 10-K Form 10-K

A report required by the SEC from exchange-listed companies that provides for annual disclosure of certain financial information.


Form 10-K

See 10-K.
 for the fiscal year ended December 31, 1997 filed with the Securities Exchange Commission.

             ARIAD PHARMACEUTICALS, INC. AND SUBSIDIARIES
            CONDENSED CONSOLIDATED STATEMENTS OF OPERATIONS

                         Three Months Ended             Year Ended
                            December 31,               December 31,
                         1998         1997         1998          1997

Revenue:
 Research revenue
  (principally    $ 2,409,922  $ 2,535,360 $ 12,143,192  $  9,233,708
  related parties)
 Interest income      169,071      428,160      998,743     1,757,327
     Total revenue  2,578,993    2,963,520   13,141,935    10,991,035
Operating expenses:
 Research and
  development       8,351,435    7,089,763   35,515,270    20,286,945
 General and
  administrative      628,293      849,221    2,633,923     2,924,972
 Interest expense     106,984      145,883      480,627       410,072
     Total operating
      expenses      9,086,712    8,084,867   38,629,820    23,621,989
Equity in net loss
 of Genomics Center   436,679                   660,295
Net loss           (6,944,398)  (5,121,347) (26,148,180)  (12,630,954)
 Preferred dividends   35,616                    35,616
Net loss attributable
 to common
 stockholders     $(6,980,014) $(5,121,347)$(26,183,796) $(12,630,954)

Net loss per share
 (basic and diluted)  $ (.32)      $ (.27)     $ (1.25)       $ (.66)
Weighted average
 number of shares of
 common stock
 outstanding       21,929,483   19,303,783   20,966,586    19,252,885


             ARIAD PHARMACEUTICALS, INC. AND SUBSIDIARIES
           CONDENSED CONSOLIDATED BALANCE SHEET INFORMATION

                                 December 31,       December 31,
                                     1998               1997
Cash and marketable securities $  14,176,136      $  29,359,457
Net fixed assets                   8,049,673         11,439,370
Other assets                       8,560,131          6,610,349
Total assets                   $  30,785,940      $  47,409,176

Debt                           $   1,861,021      $   1,816,583
Other liabilities                  8,860,876         11,762,556
Total liabilities                 10,721,897         13,579,139
Long-term debt                     3,295,139          5,156,219
Deferred revenue                                        300,000
Redeemable preferred stock         5,035,616
Stockholders' equity              11,733,288         28,373,818
Total liabilities and
 stockholders' equity          $  30,785,940      $  47,409,176
COPYRIGHT 1999 Business Wire
No portion of this article can be reproduced without the express written permission from the copyright holder.
Copyright 1999, Gale Group. All rights reserved. Gale Group is a Thomson Corporation Company.

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Geographic Code:1USA
Date:Mar 9, 1999
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