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APS Granted Two Bioerodible Polymer Patents; Composition of Matter Patents Related To Its Bioerodible Polymer Technology.


REDWOOD CITY Redwood City, city (1990 pop. 66,072), seat of San Mateo co., W Calif., on San Francisco Bay; inc. 1868. Manufactures include commmunications, electrical, electronic, and medical equipment. , Calif.--(BUSINESS WIRE)--Oct. 25, 1999--

Advanced Polymer Systems, Inc. (Nasdaq: APOS APOS American Psychosocial Oncology Society
APOS After Point of Sales
APOS Acoustic Processor Operating Station
APOS Advanced Process Oriented Steering
) today announced that it has been issued US Patent 5,968,543, "Polymers with Controlled Physical State and Bioerodibility", and US Patent 5,939,453, "Poly(Ortho Ester-Poly(Ethylene Glycol ethylene glycol: see glycol.
ethylene glycol

Simplest member of the glycol family, also called 1,2-ethanediol (HOCH2CH2OH). It is a colourless, oily liquid with a mild odour and sweet taste.
) Block Copolymers". The new patents are based on inventions by Advanced Polymer Systems related to its bioerodible drug delivery systems.

The issued claims for patent 5,968,543 cover the composition and important uses of a new family of bioerodible polymers known as poly(ortho esters esters (esˑ·terz),
n.pl organic compounds synthesized from acids and alcohols, typically possessing fruity aromas.
). These polymers are designed for placement at a suitable body site where they undergo a controlled bioerosion process. They can be used as biomatrices (e.g. in orthopedic and tissue engineering applications), and can also release physically incorporated therapeutic agents in a precisely controlled manner. Current uses under investigation at Advanced Polymer Systems involve a number of areas, including, post-operative treatment of cancer, post-operative pain control, protein release and various veterinary applications.

The issued claims for patent 5,939,453 cover the composition and important uses of another family of bioerodible polymers, known as block copolymers, that use blocks of poly(ortho esters) and blocks of poly(ethylene glycol) arranged in various combinations. These polymers are designed as delivery systems for drugs, e.g. to deliver anticancer agents selectively to tumors, thus greatly decreasing systemic toxicity of conventionally administered anticancer agents.

Jack Meakem, chairman, president and CEO (1) (Chief Executive Officer) The highest individual in command of an organization. Typically the president of the company, the CEO reports to the Chairman of the Board.  of Advanced Polymer Systems commented, "We continue to build an extensive portfolio of patents and patent applications relating to relating to relate prepconcernant

relating to relate prepbezüglich +gen, mit Bezug auf +acc 
 systemic and oral drug delivery which will provide a foundation of new proprietary technologies for a variety of potential pharmaceutical applications."

Advanced Polymer Systems is a leader in polymer-based delivery systems and related technologies used primarily for skin care in ethical and over-the-counter (OTC OTC

See: Over-the-counter.


OTC

See over-the-counter market (OTC).
) pharmaceuticals personal care products. The company's Microsponge(R) and Polytrap(R) systems, which deliver active ingredients An active ingredient, also active pharmaceutical ingredient (or API), is the substance in a drug that is pharmaceutically active. Some medications may contain more than one active ingredient.  to the skin, now play an integral role in approximately 100 personal care products sold worldwide. New products and technologies under development include site-specific systems for delivering oral medications, and a family of new bioerodible polymers for implantable drug delivery.

Forward-looking Statements forward-looking statement

A projected financial statement based on management expectations. A forward-looking statement involves risks with regard to the accuracy of assumptions underlying the projections.
 

Except for historical information, this news release contains certain forward-looking statements that involve risks and uncertainties, including among others, uncertainty associated with timely approval, launch and acceptance of new products, establishment of new corporate alliances, progress in research and development programs and risks of consummation of the sale of the Company (as to which there is no assurance). Other risks and uncertainties associated with the Company's business and prospects are identified in the Company's filings with the Securities and Exchange Commission. The Company does not undertake to revise these forward-looking statements to reflect events or circumstances occurring in the future.

This release is available at http//www.advancedpolymer.com
COPYRIGHT 1999 Business Wire
No portion of this article can be reproduced without the express written permission from the copyright holder.
Copyright 1999, Gale Group. All rights reserved. Gale Group is a Thomson Corporation Company.

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Publication:Business Wire
Geographic Code:1USA
Date:Oct 25, 1999
Words:467
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