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AMGEN SEEKS WIDER ENBREL MARKETING.


Byline: Evan Pondel Staff Writer

THOUSAND OAKS Thousand Oaks, residential city (1990 pop. 104,352), Ventura co., S Calif., in a farm area; inc. 1964. Avocados, citrus, vegetables, strawberries, and nursery products are grown.  - Biotechnology giant Amgen Inc. has submitted additional clinical data about Enbrel to U.S. regulators, a move that could eventually broaden the rheumatoid arthritis rheumatoid arthritis

Chronic, progressive autoimmune disease causing connective-tissue inflammation, mostly in synovial joints. It can occur at any age, is more common in women, and has an unpredictable course.
 drug's marketing breadth.

While the drug is already approved to treat patients with moderate to severe rheumatoid arthritis, the Thousand Oaks-based company would like the label to include that ``Enbrel showed an improvement in physical functioning.''

``Enbrel will be facing stiff competition from D2E7 (a drug developed by Abbott Laboratories Abbott Laboratories (NYSE: ABT) is a diversified pharmaceuticals and health care company. It has over 65,000 employees and operates in 130 countries. The corporate headquarters are in Abbott Park, Illinois, a neighborhood of North Chicago, Illinois. ) in the near future,'' said Jennifer Chao, analyst with RBC Capital Markets RBC Capital Markets is the corporate and investment banking division of Royal Bank of Canada ("RBC"). Broker dealers
Depending on the jurisdiction, the division uses different broker dealer subsidiaries of RBC:
  • Canada: RBC Dominion Securities Inc
 in New York New York, state, United States
New York, Middle Atlantic state of the United States. It is bordered by Vermont, Massachusetts, Connecticut, and the Atlantic Ocean (E), New Jersey and Pennsylvania (S), Lakes Erie and Ontario and the Canadian province of
. ``And the strategy is to try to get as broad of a label as possible.''

Last month, Amgen applied for regulatory approval of an Enbrel manufacturing facility in Rhode Island Rhode Island, island, United States
Rhode Island, island, 15 mi (24 km) long and 5 mi (8 km) wide, S R.I., at the entrance to Narragansett Bay. It is the largest island in the state, with steep cliffs and excellent beaches.
 - an important step to alleviate shortages of the arthritis drug. The 250,000-square-foot facility stems from Amgen's $14 million purchase of Seattle-based Immunex Corp., which received approval from U.S. regulators in July.

The surge in Enbrel's popularity has ultimately led to its scant scant  
adj. scant·er, scant·est
1. Barely sufficient: paid scant attention to the lecture.

2. Falling short of a specific measure: a scant cup of sugar.
 supply. Dr. Daniel Burge, a vice president of clinical research at Amgen, said the data submitted to the Food and Drug Administration prove Enbrel's efficacy.

``And we frequently hear from patients that they've been able to resume many of their daily activities, such as brushing their hair or picking up their child, that had become impossible due to their rheumatoid arthritis,'' Burge said.

Last year, Enbrel sales accounted for $800 million, but with Amgen's marketing backing the product, the drug could generate sales of $3 billion by 2005. Immunex projected that Enbrel sales would surge as high as $4 billion by 2005.

``Helping Enbrel even more is that it has a proven track record,'' Chao said. ``And it's important to maintain the drug's success.''

Amgen shares fell 36 cents to close at $43.70 on the Nasdaq market Thursday.
COPYRIGHT 2002 Daily News
No portion of this article can be reproduced without the express written permission from the copyright holder.
Copyright 2002, Gale Group. All rights reserved. Gale Group is a Thomson Corporation Company.

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Title Annotation:Business
Publication:Daily News (Los Angeles, CA)
Geographic Code:1USA
Date:Sep 27, 2002
Words:309
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