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AMEX REPLACES FOUR STOCKS IN ITS BIOTECHNOLOGY INDEX

 AMEX REPLACES FOUR STOCKS IN ITS BIOTECHNOLOGY INDEX
 NEW YORK, April 1 /PRNewswire/ -- The American Stock Exchange


today said that it replaced four stocks in its new Biotechnology Index. The new stocks are Cambridge Biotech Corp., Enzon, Inc., Greenwich Ph9armaceuticals Inc., and Liposome Company, Inc. These stocks replace ImmunoGen Inc., Immune Response Corp., MedImmune Inc., and Mycogen Corp.
 The Amex is awaiting Securities and Exchange Commission (SEC) approval to trade options on the Index.
 The Biotechnology Index is based on 15 leading biotechnology stocks that were chosen for their representation of the industry, trading liquidity and market value.
 In its index design, the Exchange has utilized a unique equal-dollar weighting calculation method that will provide each stock in the index with a more balanced representation. This method is particularly important in rapidly developing industries such as biotechnology where new discoveries or developments can result in sharp fluctuations in a company's stock price in a very short period of time.
 The Amex's new Biotechnology Index comprises the following stocks:
 Amgen Inc. Genzyme Corp.
 Biogen, Inc. Greenwich Pharmaceuticals Inc.
 Cambridge Biotech Corp. Immunex Corp.
 Centocor, Inc. Liposome Company Inc.
 Chiron Corp. SCIOS Inc.
 Cytogen Corp. Synergen, Inc.
 Enzon Inc. Xoma Corp.
 Gensia Pharmaceuticals
 The value of the Index can be retrieved on market data machines under
ticker symbol "BTK." The Index is calculated and disseminated every 15 seconds through the Consolidated Tape Authority's Network-B.
 The Amex trades a total of 276 stock options, including 81 options on over-the-counter stocks. In addition, options are traded on five broad market indexes -- the Major Market Index (XMI), XMI LEAPS(TM) (XLT), S&P MidCap 400 Index (MID), the Institutional Index (XII) and the Japan Index (JPN) -- as well as two industry-based indexes -- the Oil Index (XOI) and the Computer Technology Index (XCI). CAPS -- capped options -- are traded on XMI and XII as well. The Exchange also trades 29 LEAPS(TM) on leading stocks which have expirations up to almost three years.
 -0- 4/1/92
 /CONTACT: Shelly Wolfe of the American Stock Exchange, 212-306-1641/ CO: American Stock Exchange ST: New York IN: MTC SU:


TS -- NY054 -- 3852 04/01/92 12:23 EST
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Copyright 1992 Gale, Cengage Learning. All rights reserved.

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Date:Apr 1, 1992
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