Printer Friendly
The Free Library
14,487,175 articles and books
Member login
User name  
Password 
 
Join us Forgot password?

ALLERGAN/SANWA KAGAKU KENKYUSHO TO DEVELOP POSURDEX IN JAPAN.


Allergan, Inc. (NYSE NYSE

See: New York Stock Exchange
:AGN AGN Again (Amateur Radio)
AGN Active Galactic Nucleus
AGN Acute Glomerulonephritis
AGN Accountants Global Network
AGN Air Gabon (ICAO code) 
), Irvine, Calif., has entered into an exclusive licensing agreement with Sanwa Kagaku Kenkyusho Co., Ltd. (Sanwa) to develop and commercialize POSURDEX(R) for the ophthalmic specialty market in Japan. POSURDEX(R) is an investigational, bioerodable, extended release implant that delivers dexamethasone dexamethasone /dex·a·meth·a·sone/ (dek?sah-meth´ah-son) a synthetic glucocorticoid used primarily as an antiinflammatory in various conditions, including collagen diseases and allergic states; it is the basis of a screening test in the  to the targeted disease site at the back of the eye for the treatment of macular edema macular edema Ophthalmology Waxing and waning retinal thickening due to the accumulation of fluid, seen in Pts with diabetic retinopathy, seen with a binocular slit lamp or stereoscopic fundus photography; while ME has no visual consequences, it is often . The companies currently estimate Japan's annual macular edema market could be over $100 million.

Under the terms of the agreement, Sanwa will be responsible for the development and commercialization of POSURDEX(R) in Japan and will incur associated costs. Sanwa will pay Allergan a royalty based on net sales Net Sales

The amount a seller receives from the buyer after costs associated with the sale are deducted.

Notes:
This amount is calculated by subtracting the following items from gross sales: merchandise returned for credit, allowances for damaged or missing goods, freight
 of POSURDEX(R) in Japan, make development and commercialization milestone payments and reimburse Allergan for certain expenses associated with Allergan's continuing conduct of POSURDEX(R) Phase III Noun 1. phase III - a large clinical trial of a treatment or drug that in phase I and phase II has been shown to be efficacious with tolerable side effects; after successful conclusion of these clinical trials it will receive formal approval from the FDA  pivotal studies outside of Japan. Allergan and Sanwa will work collaboratively on the clinical development of POSURDEX(R), as well as overall product strategy and management.

"Retinal diseases are currently the leading cause of blindness in developed countries and represent the largest unmet need in eye care," said David E.I. Pyott, Allergan's Chairman of the Board, president and CEO (1) (Chief Executive Officer) The highest individual in command of an organization. Typically the president of the company, the CEO reports to the Chairman of the Board. . "We are pleased to be working with Sanwa to bring our POSURDEX(R) technology to the Japanese market. We expect Sanwa to maximize the potential of this exceptional technology, which ultimately may benefit millions of patients."

Kazuo Yamamoto, president of Sanwa, commented, "We are very pleased to be collaborating with Allergan on the development and marketing of POSURDEX(R) in Japan. We hope this product will improve the quality of life of many patients with retinal disease that existing therapies do not treat. We will use our best efforts to bring this innovative product to patients as quickly as possible."

Allergan is currently conducting two Phase III clinical programs worldwide with POSURDEX(R) focusing on macular edema associated with diabetes and other conditions. In Japan, Sanwa is expected to begin Phase I/II development with POSURDEX(R) later this year.

By 2010, the global ophthalmic market for retinal diseases is currently estimated to be over $3.7 billion annually. Aging populations are anticipated to lead to increasing numbers of patients at risk for these diseases. Japan's elderly population is currently the largest among industrialized in·dus·tri·al·ize  
v. in·dus·tri·al·ized, in·dus·tri·al·iz·ing, in·dus·tri·al·iz·es

v.tr.
1. To develop industry in (a country or society, for example).

2.
 nations (18.5%, Ministry of Health, Labour and Welfare (MHLW MHLW Ministry of Health, Labor and Welfare (Japan; formerly Ministry of Health and Welfare, MHW)
MHLW Mean High Low Water (tide level) 
), 2002) and projected to account for more than 33% of Japan's total population by 2050. The increasing incidence of diabetes is also significantly adding to the retina market's growth potential. A 2002 survey by the World Health Organization estimates there will be as many as 300 million diabetics worldwide by 2025, up from approximately 50 million in 2002. In Japan, 7.4 million people are suspected to have diabetes (MHLW, 2002).

Macular edema is a sight-threatening condition that results from the swelling of the central retina, or macula, and is associated with diseases such as diabetic retinopathy diabetic retinopathy
n.
Retinal changes occurring in long-term diabetes and characterized by punctate hemorrhages, microaneurysms, and sharply defined waxy exudates.
, retinal vein occlusion Retinal Vein Occlusion Definition

Retinal vein occlusion refers to the closure of the central retinal vein that drains the retina or to that of one of its branches.
 and uveitis uveitis

Inflammation of the uvea, the middle coat of the eyeball. Anterior uveitis, involving the iris or ciliary body (containing the muscle that adjusts the lens) or both, can lead to glaucoma and blindness.
. Macular edema is a major cause of visual disabilities and blindness among individuals with diabetes. Allergan estimates that macular edema currently affects more than 750,000 people in the United States, and over 2.5 million people worldwide. A significant share of these patients has persistent macular edema that has failed to respond to the current standard of care.

About Allergan, Inc.

Allergan, Inc., with headquarters in Irvine, California, is a technology-driven, global health care company providing specialty pharmaceutical products worldwide. Allergan develops and commercializes products in the eye care, neuromodulator, skin care and other specialty markets that deliver value to its customers, satisfy unmet medical needs, and improve patients' lives.

About Sanwa Kagaku Kenkyusho Co., Ltd.

Sanwa, a division of Suzuken, the second largest pharmaceutical wholesaler in Japan, is a fully-integrated pharmaceutical company headquartered in Nagoya, Japan with established therapeutic and diagnostic products serving the diabetes, cardiovascular, and inflammation marketplaces. Sanwa's mission is to develop and bring to the patients "patient-friendly" medicines that contribute to an improved quality of life on a cost-effective basis.

For more information, call 714/246-4636.
COPYRIGHT 2005 Worldwide Videotex
No portion of this article can be reproduced without the express written permission from the copyright holder.
Copyright 2005, Gale Group. All rights reserved. Gale Group is a Thomson Corporation Company.

 Reader Opinion

Title:

Comment:



 

Article Details
Printer friendly Cite/link Email Feedback
Publication:Worldwide Biotech
Geographic Code:9JAPA
Date:May 1, 2005
Words:675
Previous Article:INDIA AND CII SUPPORT AETHLON HIV/HEPATITIS TRIALS.
Next Article:MONSANTO ENCOURAGED BY BRAZILIAN BIOSAFETY LAW.
Topics:



Related Articles
New leader, new status. (Tamio Takakura, chief executive officer of Sanwa Bank California)
ALLERGAN LICENSES QUINOLONE ANTIBIOTIC FROM KYORIN.
Sanwa Bank Awarded $31 Million in Bizarre Lawsuit.
SEEING GREEN IN GOLDEN STATE SANWA BANK'S DEEP ROOTS BRING STEADY GROWTH, ACROSS CALIFORNIA.(Business)
SANWA, TOKAI TO MERGE RIVALS COMBINING AS UNITED CALIFORNIA BANK.(Business)
RIKEN, Perlegen Sciences Japan to Collaborate in High-resolution Whole Genome Studies.
Matsushita Ecology System Develops Bacteriological Test System for Raw Milk.
Sanwa Kagaku Kenkyusho Introduces Safety-engineered Blood Sampling Device and Disposable Needle.
Sanwa Kagaku Kenkyusho Obtains Manufacturing Approval for Sable, Postprandial Glucose Controlling Agent.
Sanwa Kagaku Kenkyusho Releases SEIBULE, Miglitol Agent for Controlling Postprandical Blood Glucose.

Terms of use | Copyright © 2009 Farlex, Inc. | Feedback | For webmasters | Submit articles