AIST Announces Discovery of New Quality-Control Mechanism for Proteins Synthesized in Cells.Tokyo, Japan, Jan 11, 2006 - (JCN) - The National Institute of Advanced Industrial Science and Technology The National Institute of Advanced Industrial Science and Technology (産業技術総合研究所 (AIST) and the University of Tsukuba The current university was established in October, 1973. A forerunner of this university was Tokyo University of Education (東京教育大学 (President: Yoichi Iwasaki) found a new mechanism to exclude abnormal proteins by designing an unusual protein which is not adequately folded in the cell. A group of proteins with glycolipids, called "GPI (Graphical Programming Interface) A graphics language in OS/2 Presentation Manager. It is a derivative of the GDDM mainframe interface and includes Bezier curves. anchors," exist in cells. In this work, we have found a new quality-control mechanism for these proteins using an artificially designed abnormal protein in cell. This finding may contribute to the development of new curative medicines for fungal infections, e.g., candidiasis candidiasis (kăn'dĭdī`əsĭs), infection of the mucous membranes caused by the fungus Candida albicans. Other terms for candidiasis are yeast infection, moniliasis (after a former name of the fungal genus), and thrush, the . Moreover, this can be expected to clarify the onset mechanisms of incurable diseases such as prion disease and hypophosphatasia, leading to the development of medical treatments. The details of this work were published in the electronic edition of the US international journal "Molecular Biology of the Cell Molecular Biology of the Cell (MBC) is a scientific journal published monthly online and in print by the American Society for Cell Biology. MBC publishes original and scholarly research reports that contribute to the scientific understanding of the molecular basis of cell structure " on November 30, 2005. Copyright [c] 2006 Japan Corporate News Network. All rights reserved. |
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