ADVISORY/Eisai Expands Research Triangle Park Facility.

Business Editors

ADVISORY...for June 12 (Weds.)

--(BUSINESS WIRE)

Eisai Inc.:

      WHAT:       Eisai Inc., a Teaneck, N.J.-based pharmaceutical
                company, broke ground today for a significant
                expansion of its manufacturing and research and
                development site in Research Triangle Park, North
                Carolina. The 80,000 square foot expansion, which will
                nearly double the size of the original facility
                dedicated in 1997, is planned to increase the
                company's manufacturing and packaging capabilities.

                  In the past five years, Eisai has gained a foothold in
                the U.S. market through strategic copromotion
                agreements for its innovative therapies and is now
                moving toward in-licensing and independent marketing
                of products.

                  The company had an initial plan to expand the facility
                every three to five years. The first expansion,
                completed in May 2001, was expected to meet Eisai's
                space requirements for the next two to four years.
                However, growth has been faster than anticipated. Upon
                completion of this second expansion, Eisai's Research
                Triangle Park facility will lead to new job
                opportunities over the next two years.

      WHEN:       Wednesday, June 12
                Noon - Groundbreaking Ceremony

      WHERE:      Eisai Inc., 900 Davis Dr., Research Triangle Park

      WHO:        Haruo Naito, President and CEO, Eisai Co., Ltd.
                (parent company of Eisai Inc.)

                  Soichi Matsuno, Chairman and CEO, Eisai Inc.

                  William Sheldon, President and COO, Eisai Inc.

                  James Fain, North Carolina Secretary of Commerce

                  Jim Roberson, President and CEO, Research Triangle
                Foundation of North Carolina

                  Larry Kranking, Vice President and General Manager of
                Eisai Inc./RTP

                  Ray Wood, Vice President, Pharmaceutical & Analytical
                Research and Development, Eisai Inc.

                  INTERVIEW AND PHOTO OPPORTUNITIES:

                           Tuesday, June 11
                          Wednesday, June 12