ADVISORY/ HTS Biosystems & Applied Biosystems to Present Research on Next-Generation Protein Affinity Array Technology at IBC's Annual International Conference on Antibody Engineering.

Business Editors & Health/Medical Writers

BIOWIRE2K

ADVISORY for ... Sunday and Monday (Dec. 1-2)

--(BUSINESS WIRE)

Who/What:            New research on HTS Biosystems' and Applied
                     Biosystems' proprietary biomolecular kinetic
                     analysis technology will be presented at IBC Life
                     Sciences' 13th Annual International Conference on
                     Antibody Engineering (December 1-4, 2002). This
                     next-generation microarray-based SPR (surface
                     plasmon resonsance) system is designed to help
                     researchers profile and characterize biomolecular
                     interactions in a parallel format, while
                     decreasing costs associated with this productive
                     type of quantitative analysis.

                     Highlights:

                     -    Early access users of the technology, the
                          University of Utah and Dyax Corp., will
                          present their preliminary utility experience
                          with the system.

                     -    Demonstrations of the technology's user
                          interface will be offered at the Applied
                          Biosystems booth at the conference.

Why:                 -    The Antibody Engineering Meeting will
                          enable HTS Biosystems and Applied Biosystems
                          to showcase their progress in the
                          development of advanced, label-free SPR
                          array technology designed to accelerate drug
                          discovery R&D with higher throughput,
                          content-rich biomolecular binding
                          characterization screening.



Where:               Paradise Point Resort
                     1404 Vacation Road
                     San Diego, CA 92109

When:                The oral research presentations include:

                     -    Sunday, December 1, 1:40 p.m. (PST):
                          Affinity Biosensing to the nth Degree
                          (Dr. David Myszka, Center for Biomolecular
                          Interaction Analysis, University of Utah)

                     -    Monday, December 2, 4:30 p.m. (PST):
                          A Microarray-Based Surface Plasmon Resonance
                          Method For the Rapid Determination of Phage
                          Display Derived Human Antibody Dissociation
                          Constants
                          (Dr. Dan Sexton, Investigator, Dyax
                          Corporation)

                     Data from the abstracts are embargoed to the
                     press until after each presentation. For more
                     information, or to obtain a copy of the abstract,
                     please visit:
                     http://www.lifesciencesinfo.com/antibodyeng


About HTS            HTS Biosystems, Inc. is a privately held
Biosystems:          biotechnology company specializing in
                     high-throughput bioanalytical systems for the
                     rapidly growing field of proteomics. HTS
                     Biosystems offers a unique portfolio of
                     innovative technologies that support all phases
                     of proteomics, from discovery to development of
                     therapeutic and diagnostic products. The
                     company's technology platform - the
                     Proteomatrix(TM) Solution - streamlines the
                     discovery process and captures fixed costs for
                     more effective use of protein data in target
                     screening, validation, and discovery efforts.
                     Collaborations with key industry partners, such
                     as Applied Biosystems, Dyax Corporation,
                     Mitsubishi Chemical Corporation, and Molsoft LLC
                     have driven the development of the company's
                     technologies and related systems, including the
                     joint HTS Biosystems-Applied Biosystems
                     next-generation SPR array technology platform,
                     the CHEMI FLEX(TM) System, and the PHASE FLEX(TM)
                     System for target discovery, screening and
                     validation. HTS Biosystems' operations are
                     located in Hopkinton, MA. For more information,
                     visit www.htsbiosystems.com

About Applied        Applied Biosystems, a business unit of Applera
Biosystems:          Corporation, develops and markets
                     instrument-based systems, reagents, software, and
                     contract related services to the life science
                     industry and research community. These
                     technologies enable biological discoveries in
                     life science research, pharmaceutical research
                     and development, diagnostics, and agriculture.
                     Its broad portfolio of technologies, which
                     includes DNA sequencing, PCR, organic synthesis,
                     chemiluminescence, mass spectrometry, and
                     information management systems, enable genomics,
                     proteomics, high throughput screening, and other
                     molecular analyses. For more information, visit:
                     http://www.appliedbiosystems.com