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A study of prognostic factors in sudden hearing loss.


We investigated the prognostic significance of the presence or absence of vertigo and tinnitus Tinnitus Definition

Tinnitus is hearing ringing, buzzing, or other sounds without an external cause. Patients may experience tinnitus in one or both ears or in the head.
, the timing of the initiation of treatment, the type and severity of hearing loss, and age in 72 patients who had experienced sudden hearing loss. We found that the factors associated with a positive prognosis were the absence of vertigo, the presence of tinnitus, initiation of treatment within 7 days, a greater degree of hearing loss in the low frequencies, and a hearing loss of less than 45 dB. Age had no effect on prognosis.


Sudden hearing loss is defined as a sensorineural sensorineural /sen·so·ri·neu·ral/ (-noor´al) of or pertaining to a sensory nerve or mechanism; see also under deafness.

 hypoacusis of at least 30 dB in 3 consecutive speech frequencies that has occurred within the previous 3 days. (1,2) Its worldwide incidence has been reported to range from 5 to 20 cases per 100,000 population. (2) The reported incidence is lowest in patients aged 20 to 30 years (4.7 per 100,000) and highest in those aged 50 to 60 years (15.8 per 100,000). (3) Since some patients experience a spontaneous resolution of their deafness and therefore do not seek treatment, the actual incidence is higher. (2) Sudden hearing loss affects the two sexes equally. Approximately 90% of cases are unilateral. (4)

Studies of the etiology of sudden hearing loss have focused on four possible causes: (1) circulatory anomalies (e.g., thrombosis, vasospasm vasospasm /vaso·spasm/ (va´zo-) (vas´o-spazm) angiospasm; spasm of blood vessels, causing vasoconstriction.vasospas´tic

, and embolism embolism

Obstruction of blood flow by an embolus—a substance (e.g., a blood clot, a fat globule from a crush injury, or a gas bubble) not normally present in the bloodstream. Obstruction of an artery to the brain may cause stroke.
), (2) viral labyrinthitis Labyrinthitis Definition

Labyrinthitis is an inflammation of the inner ear that is often a complication of otitis media. It is caused by the spread of bacterial or viral infections from the head or respiratory tract into the inner ear.
 or viral infection viral infection,
n an infection by a pathogenic virus. A virus acts on the cell nucleus, taking over the genetic material within the nucleus and replicating itself.
 of the cochlea cochlea (kŏk`lēə): see ear. , (3) irregularities of the cochlear cochlear

pertaining to or emanating from the cochlea.

cochlear duct
the coiled portion of the membranous labyrinth located inside the cochlea; contains endolymph.

cochlear nerve
see Table 14.
 membrane, and (4) autoimmune disorders Autoimmune Disorders Definition

Autoimmune disorders are conditions in which a person's immune system attacks the body's own cells, causing tissue destruction.
. (4) Support exists for each of these explanations, but the most popular theory is that sudden deafness sudden deafness Audiology An abrupt hearing loss that follows a known cause of deafness–eg, an explosion, viral infection, or use of certain drugs  is caused by a disturbance of the cochlear blood flow. (5) Support for this theory is based on histopathologic findings, the suddenness of the hearing loss, and the fact that affected patients often have concomitant vascular disease. (6,7)

Many studies have been conducted to identify factors that may have a positive or negative effect on patients with sudden hearing loss. (3,8-10) We conducted our own study to test the reliability of these previously investigated variables.

Patients and methods

Between Jan. 2, 1999, and Dec. 31, 2002, 107 patients were diagnosed with sudden hearing loss in the Department of Otorhinolaryngology otorhinolaryngology /oto·rhi·no·lar·yn·gol·o·gy/ (-ri?no-lar?ing-gol´ah-je) the branch of medicine dealing with the ear, nose, and throat.

 at the Cerrahpasa Medical School and at a private hyperbaric oxygen therapy Hyperbaric oxygen therapy (HBO)
A treatment in which the patient is placed in a chamber and breathes oxygen at higher-than-atmospheric pressure. This high-pressure oxygen stops bacteria from growing and, at high enough pressure, kills them.
 center. Of this group, 72 patients had been treated with 1 mg/kg of fluocortolone with dose reductions of 10 mg every 3 days, 100-mg ampules of pentoxifylline three times a day for 15 days, 500 ml of dextran dextran /dex·tran/ (dek´stran) a high-molecular-weight polymer of d-glucose, produced by enzymes on the cell surface of certain lactic acid bacteria.  once a day for 3 days, and hyperbaric oxygen therapy for 2 weeks. These 72 patients--39 males (54.2%) and 33 females (45.8%), aged 10 to 72 years (mean: 36.94 [+ or -] 15.24)--were included in our study; the remaining 35 patients received different treatment and were not included.

We investigated the prognostic significance of the presence or absence of vertigo and tinnitus, the timing of the initiation of treatment, the type and severity of hearing loss, and age. To that end, we obtained a history from each patient, with emphasis on how and when the hearing loss had begun, the presence or absence of accompanying vertigo and tinnitus, and the onset of treatment. Patients also underwent audiometry (125 to 8,000 Hz) and tympanometry, as well as determinations of speech perception thresholds, speech discrimination scores, and acoustic reflexes. Magnetic resonance imaging magnetic resonance imaging (MRI), noninvasive diagnostic technique that uses nuclear magnetic resonance to produce cross-sectional images of organs and other internal body structures.  (MRI 1. (application) MRI - Magnetic Resonance Imaging.
2. MRI - Measurement Requirements and Interface.
) of the cranium cranium: see skull.  was performed on all patients. We also performed routine ENT ENT ears, nose, and throat (otorhinolaryngology).

ear, nose, and throat


ear, nose and throat.

ENT Ears, nose & throat; formally, otorhinolaryngology
 and otoneurologic examinations and ordered biochemical testing Biochemical testing
Measuring the amount or activity of a particular enzyme or protein in a sample of blood or urine or other tissue from the body.

Mentioned in: Von Willebrand Disease
, which included measurements of the total blood count, erythrocyte sedimentation rate Erythrocyte Sedimentation Rate Definition

The erythrocyte sedimentation rate (ESR), or sedimentation rate (sed rate), is a measure of the settling of red blood cells in a tube of blood during one hour.
, C-reactive protein C-Reactive Protein Definition

C-reactive protein (CRP) is a protein produced by the liver and found in the blood.

C-reactive protein is not normally found in the blood of healthy people.
 level, prothrombin time Prothrombin Time Definition

The prothrombin time test belongs to a group of blood tests that assess the clotting ability of blood. The test is also known as the pro time or PT test.
, activated partial thromboplastin time Activated partial thromboplastin time
Partial thromboplastin time test that uses activators to shorten the clotting time, making it more useful for heparin monitoring.
, bleeding and coagulation coagulation (kōăg'ylā`shən), the collecting into a mass of minute particles of a solid dispersed throughout a liquid (a sol), usually followed by the precipitation or  times, aspartate aspartate /as·par·tate/ (ah-spahr´tat) a salt of aspartic acid, or aspartic acid in dissociated form.

1. A salt of aspartic acid.

 and alanine transaminase alanine transaminase /al·a·nine trans·am·i·nase/ (trans-am´i-nas) an enzyme normally present in serum and body tissues, especially in the liver; it is released into the serum as a result of tissue injury, hence the concentration in the  levels, blood lipid concentrations, thyroid function, rheumatoid factor rheumatoid factor
n. Abbr. RF
Any of the immunoglobulins found in the serum of individuals with rheumatoid arthritis that enhance the agglutination of suspended particles that are coated with pooled human gamma globulin and that are used
 level, and antinuclear antibody an·ti·nu·cle·ar antibody
n. Abbr. ANA
An antibody that attacks cell nuclei.

antinuclear antibody,
 level. In addition, serologic se·rol·o·gy  
n. pl. se·rol·o·gies
1. The science that deals with the properties and reactions of serums, especially blood serum.

 investigations for hepatitis B Hepatitis B Definition

Hepatitis B is a potentially serious form of liver inflammation due to infection by the hepatitis B virus (HBV). It occurs in both rapidly developing (acute) and long-lasting (chronic) forms, and is one of the most common chronic
 and C virus, human immunodeficiency virus human immunodeficiency virus

Human immunodeficiency virus (HIV)
A transmissible retrovirus that causes AIDS in humans.
 (HIV HIV (Human Immunodeficiency Virus), either of two closely related retroviruses that invade T-helper lymphocytes and are responsible for AIDS. There are two types of HIV: HIV-1 and HIV-2. HIV-1 is responsible for the vast majority of AIDS in the United States. ), and syphilis were obtained.

We classified patients into various groups according to possible prognostic factors:

* vertigo-positive and vertigo-negative patients

* tinnitus-positive and tinnitus-negative patients

* patients whose treatment had been initiated within 7 days of the onset of sudden hearing loss and those who had been treated 8 days afterward or beyond

* patients with specific types of hearing loss as determined by audiometric au·di·om·e·ter  
An instrument for measuring hearing activity for pure tones of normally audible frequencies. Also called sonometer.

 curve patterns: ascending (hearing loss greater at the lower frequencies), flat, descending (hearing loss greater at the higher frequencies), and total

* age: two primary age groups ([less than or equal to] 40 and [greater than or equal to] 41 yr), further subclassified into five secondary groups ([less than or equal to] 15 yr, 16 to 30, 31 to 45, 46 to 60, and [greater than or equal to] 61)

We then determined the degree of hearing recovery in each group. (11) Recovery was rated on a scale of 1 to 4:

* 1: complete recovery (hearing threshold: <20 dB)

* 2: moderate recovery (hearing gain: [greater than or equal to] 30 dB)

* 3: slight recovery (hearing gain: 11 to 29 dB)

* 4: no recovery (hearing gain: 0 to 10 dB)

Statistical comparisons among groups were based on the Mann-Whitney U test Mann-Whitney U test, See test, Mann-Whitney U.
 and the Kruskal-Wallis test. Because deviations in hearing loss and gain were wide and determinations of hearing gain were based on an artificially precise recovery score, we also compared groups according to nonparametric tests. In addition, we also used nonparametric tests in cases in which the number of patients in a group was small (e.g., the [greater than or equal to] 61-yr age group; n = 3). As a result, our data were calculated as both median values and as standard deviations from the mean. The chi-square test was used to compare categoric parameters with each other.


None of the serology tests for hepatitis B and C virus, HIV, and syphilis was positive. No acoustic neuroma was found on MRI.

Vertigo. Hearing recovery was significantly better in the vertigo-negative group (p < 0.05) (table 1).

Tinnitus. The presence of tinnitus was associated with significantly greater hearing recovery (p < 0.05) (table 1).

Time to treatment. Patients who had begun treatment 7 days or earlier after the onset of their hearing loss experienced significantly greater recovery (p < 0.05) (table 1).

Type of hearing loss. Significantly better recovery was seen in patients with ascending curves than in those with flat audiograms, descending curves, and total hearing loss (all p < 0.05) (table 1). No significant differences were seen among the groups with flat audiograms, descending curves, and total hearing loss.

Severity of hearing loss. Analysis of recovery rates according to specific measurements of the severity of hearing loss (i.e., 30 to 45 dB, 46 to 90 dB, and [greater than or equal to] 91 dB) revealed a statistically significant difference in favor of those with less severe hearing loss (p < 0.01) (table 2).

Age. Analysis of recovery according to the five age subcategories revealed no significant differences among groups (table 1). Analysis of patients according to the two primary age categories ([less than or equal to] 40 and [greater than or equal to] 41 yr) showed that the mean hearing gain was 28.21 dB ([+ or -] 26.54) in the younger group and 21.53 dB ([+ or -] 24.29) in the older group--not a statistically significant difference. Among the 42 patients in the younger group, recovery was complete in 14 (33.3%), moderate in 8 (19.0%), and slight in 5 (11.9%); 15 of these patients (35.7%) experienced no recovery. Corresponding figures among the older group (n = 30) were 12 (40.0%), 7 (23.3%), 4 (13.3%), and 7 (23.3%). Again, no statistically significant difference in recovery rates was seen between the two primary age groups.


Although sudden hearing loss has been an ongoing problem throughout history, its etiopathogenesis is still not completely clear. More than 100 possible causes have been implicated im·pli·cate  
tr.v. im·pli·cat·ed, im·pli·cat·ing, im·pli·cates
1. To involve or connect intimately or incriminatingly: evidence that implicates others in the plot.

 over the years, but most cases remain idiopathic. (3,12) Many studies of the prognosis of affected patients have centered on the same parameters that we investigated in our study: the presence or absence of vertigo and tinnitus, the timing of the initiation of treatment, the type and severity of hearing loss, and age. (3,8-10)

The presence of vertigo, which has been reported to occur in as many as 40% of patients with sudden hearing loss, has previously been shown to be a negative prognostic factor. (8,13) Affected patients usually complain of aural fullness, pressure, and awareness of a humming sound. (3,7,12) Moskowitz et al reported that the presence of vertigo indicates a poor prognosis; they found that only 14% of patients they studied achieved a complete recovery of hearing. (8) Shiraishi et al reported a complete, moderate, or slight recovery in 40% of vertiginous ver·tig·i·nous
1. Affected by vertigo; dizzy.

2. Tending to produce vertigo.

vertiginous adjective Related to vertigo, dizzy
 patients with sudden hearing loss. (14) Saeki and Kitahara reported a complete, moderate, or slight recovery in 70% of patients with no vertigo and no abnormal findings on electronys-tagmography. (9) Our findings are consistent with those in these previous reports. In our study, 26 of the 72 patients (36.1%) were vertigo-positive, and only 6 of them (23.1%) achieved a complete recovery. However, almost one-half of the 46 vertigo-negative patients experienced only a slight recovery or none at all.

Tinnitus has been reported to accompany sudden hearing loss in 75% of patients, and its presence is considered to be a positive prognostic indicator. (9) Our findings were consistent with those in the literature, as tinnitus was present in 53 of our patients (73.6%), and a complete recovery was achieved in a significantly greater proportion of patients who had tinnitus (37.7%) than in those who did not (10.5%). Even so, more than one-half of our tinnitus-positive patients experienced only a slight recovery or none at all.

It is a common opinion that the treatment of sudden hearing loss should generally begin within 10 weeks. As one would expect, earlier treatment is associated with a better prognosis. (8,10,15,16) All patients in our study had come to us within 1 month of the onset of sudden hearing loss; 50 of them (69.4%) had presented to us during the first 7 days. This figure is consistent with those reported by Shiraishi et al (14) and Kronenberg et al. (17) Shaia and Sheehy reported that a complete, moderate, or slight recovery was achieved in 75% of patients who had been treated with a vasodilator vasodilator /vaso·di·la·tor/ (-di-la´ter)
1. causing dilatation of blood vessels.

2. a nerve or agent that does this.

 within 7 days; the recovery rate dropped to 53% among those who had presented 1 week to 1 month after the onset of their hearing loss. (10) Likewise, Moskowitz et al reported a 56% rate of complete, moderate, or slight recovery with steroid treatment within 7 days and a 27% recovery rate thereafter; they also noted that recovery occurred in 68% of patients who were treated within 3 days. (8) Finally, Byl reported a first-week recovery rate of 56%. (3) The recovery rates of patients who had been treated during the first week in our study were both at variance with and consistent with those reported by others. We observed a complete recovery in 19 of the 50 patients (38.0%) who had been treated during the first week (vs. 56% reported by Byl (3)), while 35 patients (70.0%) experienced either a complete, moderate, or slight recovery (vs. 75% reported by Shaia and Sheehy (10) and 56% reported by Moskowitz et al (8)). Also in our study, 11 of 22 patients (50.0%) who had been treated beyond 1 week of the onset of sudden deafness experienced no recovery, a rate that is consistent with the failure rate of 53% reported by Shaia and Sheehy. (10) Overall, our findings with respect to the benefit of early treatment are consistent with those reported in the literature.

Others have reported that the prognosis is good for patients whose audiogram au·di·o·gram
A graphic record of hearing ability for various sound frequencies.

A chart or graph of the results of a hearing test conducted with audiographic equipment.
 curves are ascending or flat and poor for those with descending curves. (5,8,18,19) Reported rates of spontaneous recovery at low frequencies (ascending curves) range from 40 to 66%. (3) We also found that patients with ascending curves experienced significantly better recovery than did those with other audiographic findings.

Recovery is also influenced by the severity of sudden hearing loss. (8) Ustun et al reported that the prognosis for recovery was very poor in patients whose hearing loss was total. (16) Kronenberg et al found that only 22% of patients with a total hearing loss experienced a complete, moderate, or slight recovery following treatment with a vasoactive vasoactive /vaso·ac·tive/ (va?zo-) (vas?o-ak´tiv) exerting an effect upon the caliber of blood vessels.

 agent. (17) Shiraishi et al reported a complete, moderate, or slight recovery in 38% of patients with a severe hearing loss. (14) Byl reported complete, moderate, or slight recovery in 83% of patients with a severe heating loss and only 22% among those with a total hearing loss following steroid treatment. (3) Again, our findings were consistent with those in the literature. (3,17) We observed no recovery in 12 of 15 patients (80.0%) with a total hearing loss (the remaining 3 patients experienced a moderate recovery). On the other hand, all 7 of our patients whose hearing loss was in the range of 30 to 45 dB recovered completely. Recovery rates among those whose hearing loss was more severe were significantly worse. Again, our findings are consistent with those of others.

No consensus exists in the literature as to the prognostic importance of age. Megighian et al found that the highest incidence of sudden hearing loss occurred in patients aged 30 to 60 years, and they suggested that age is a prognostic factor. (15) Others consider age to be irrelevant. (8) We also found the highest incidence of sudden hearing loss occurred in patients aged 31 to 60 years (62.5%), but the difference between this group and other age groups was not statistically significant.

In conclusion, we found that a good prognosis for patients with sudden heating is associated with the absence of vertigo, the presence of tinnitus, early treatment, a hearing loss in the lower frequencies, and a hearing loss of 45 dB or less. We found no evidence to suggest that age has any influence on prognosis.


(1.) Eisenman D, Arts HA. Effectiveness of treatment for sudden sensorineural hearing loss Sensorineural hearing loss
Hearing loss caused by damage to the nerves or parts of the inner ear governing the sense of hearing.

Mentioned in: Tinnitus

sensorineural hearing loss 
. Arch Otolaryngol Head Neck Surg 2000;126:1161-4.

(2.) Byl FM. Seventy-six cases of presumed sudden hearing loss occurring in 1973: Prognosis and incidence. Laryngoscope 1977;87: 817-25.

(3.) Byl FM, Jr. Sudden hearing loss: Eight years' experience and suggested prognostic table. Laryngoscope 1984;94:647-61.

(4.) Ogasawara H, Morimoto K, Ishii K, et al. [A statistical analysis of sudden deafness]. Nippon Jibiinkoka Gakkai Kaiho 1993;96: 914-21.

(5.) Kallinen J, Laurikainen E, Laippala P, Grenman R. Sudden deafness: A comparison of anticoagulant therapy and carbogen inhalation therapy. Ann Otol Rhinol Laryngol 1997;106:22-6.

(6.) Canakcioglu S, Papila I, Altug T, Camur O. Ani isitme kayiplarinin degerlendirilmesi. Turk ORL ORL Oto-Rhino Laryngologie (France)
ORL Orlando Executive Airport (Airport Code)
ORL Optical Return Loss
ORL Journal for Oto-Rhino-Laryngology and its related specialties
 Arsivi 1991;29:142-4.

(7.) Nomura Y. Diagnostic criteria for sudden deafness, mumps deafness and perilymphatic perilymphatic /peri·lym·phat·ic/ (-lim-fat´ik)
1. pertaining to the perilymph.

2. around a lymphatic vessel.

 fistula fistula (fĭs`chlə), abnormal, usually ulcerous channellike formation between two internal organs or between an internal organ and the skin. . Acta Otolaryngol Suppl 1988;456:7-8.

(8.) Moskowitz D, Lee KJ, Smith HW. Steroid use in idiopathic sudden sensorineural hearing loss. Laryngoscope 1984;94:664-6.

(9.) Saeki N, Kitahara M. Assessment of prognosis in sudden deafness. Acta Otolaryngol Suppl 1994;510:56-61.

(10.) Shaia FT, Sheehy JL. Sudden sensori-neural hearing impairment: A report of 1,220 cases. Laryngoscope 1976;86:389-98.

(11.) Einer H, Tengborn L, Axelsson A, Edstrom S. Sudden sensorineural hearing loss and hemostatic hemostatic /he·mo·stat·ic/ (he?mo-stat´ik)
1. causing hemostasis, or an agent that so acts.

2. due to or characterized by stasis of the blood.

 mechanisms. Arch Otolaryngol Head Neck Surg 1994;120:536-40.

(12.) Shikowitz MJ. Sudden sensorineural hearing loss. Med Clin North Am 1991;75:1239-50.

(13.) Harris JP, Ruckenstein MJ. Sudden sensorineural heating loss, perilymph fistula and autoimmune inner ear disease. In: Ballenger JJ, Snow JB, Jr, eds. Otorhinolaryngology: Head and Neck Surgery. Baltimore: Williams & Wilkins, 1996:1109-18.

(14.) Shiraishi T, Kubo T, Okumura S, et al. Hearing recovery in sudden deafness patients using a modified defibrinogenation therapy. Acta Otolaryngol Suppl 1993;501:46-50.

(15.) Megighian D, Bolzan M, Barion U, Nicolai P. Epidemiological considerations in sudden hearing loss: A study of 183 cases. Arch Otorhinolaryngol 1986;243:250-3.

(16.) Ustun O, Tekin M, Alkaya Z, et al. Ani isitme kayiplarinda steroid ve urografin tedavisi sonuclarinin karsilastirilmasi. KBB KBB Kelley Blue Book
KBB Koninklijke Bijenkorf Beheer
KBB Kulak Burun Bogaz (Turkish: Ear, Nose & Throat)
KBB Kelly Bell Band
KBB Kim Basinger Band
KBB Kentucky Backroads Band (band) 
 Ihtisas Dergisi 1999;6:218-21.

(17.) Kronenberg J, Almagor M, Bendet E, Kushnir D. Vasoactive therapy versus placebo in the treatment of sudden hearing loss: A double-blind clinical study. Laryngoscope 1992;102:65-8.

(18.) Mattox DE, Lyles CA. Idiopathic sudden sensorineural hearing loss. Am J Otol 1989;10:242-7.

(19.) Menotti A, Kromhout D, Blackburn H, et al. Food intake patterns and 25-year mortality from coronary heart disease coronary heart disease: see coronary artery disease.
coronary heart disease
 or ischemic heart disease

Progressive reduction of blood supply to the heart muscle due to narrowing or blocking of a coronary artery (see atherosclerosis).
: Cross-cultural correlations in the Seven Countries Study. The Seven Countries Study Research Group. Eur J Epidemiol 1999;15:507-15.

Aydin Mamak, MD; Suleyman Yilmaz, MD; Harun Cansiz, MD; Ender Inci, MD; Ender Guclu, MD; Levent Derekoylu, MD

From the Department of Otorhinolaryngology, Cerrahpasa Medical School, University of Istanbul.

Reprint requests: Suleyman Yilmaz, MD, Istanbul Universitesi Cerrahpasa, Tip Fak KBB ABD ABD  
A candidate for a doctorate who has completed all the requirements for the degree, such as courses and examinations, with the exception of the dissertation.

[a(ll) b(ut) d(issertation).]
, Istanbul, Turkey. Phone: 90-216-576-7012; fax: 90-216-469-5338; e-mail:
Table 1. Recovery rates according to the presence or absence of vertigo
and tinnitus, time to initiation of treatment, type of hearing loss,
and age

                                                  Complete    Moderate
Prognostic                           Patients,   recovery,    recovery,
factor                                   n         n (%)        n (%)

  Positive                              26        6 (23.1)     1 (3.8)
  Negative                              46       16 (34.8)     8 (17.4)

  Positive                              53       20 (37.7)     6 (11.3)
  Negative                              19        2 (10.5)     4 (21.1)

Time to treatment
  [less than or equal to] 7 days        50       19 (38.0)     8 (16.0)
  [greater than or equal to] 7 days     22        3 (13.6)     1 (4.5)

Type of H L
  Ascending                             17       12 (70.6)     2 (11.8)
  Flat                                  14        6 (42.9)     1 (7.1)
  Descending                            26        4 (15.4)     3 (11.5)
  Total                                 15        0            3 (20.0)

Age (yr)
  [less than or equal to] 15             6        2 (33.3)     1 (16.7)
  16 to 30                              20        8 (40.0)     3 (15.0)
  31 to 45                              24        7 (29.2)     3 (12.5)
  46 to 60                              19        5 (26.3)     1 (5.3)
  [greater than or equal to] 61          3        0            1 (33.3)

Prognostic                           recovery,  No recovery,
factor                                 n (%)       n (%)

  Positive                            8 (30.8)    11 (42.3)
  Negative                            7 (15.2)    15 (32.6)

  Positive                           11 (20.8)    16 (30.2)
  Negative                            3 (15.8)    10 (52.6)

Time to treatment
  [less than or equal to] 7 days      8 (16.0)    15 (30.0)
  [greater than or equal to] 7 days   7 (31.8)    11 (50.0)

Type of H L
  Ascending                           1 (5.9)     2 (11.8)
  Flat                                2 (14.3)    5 (35.7)
  Descending                         12 (46.2)    7 (26.9)
  Total                               0          12 (80.0)

Age (yr)
  [less than or equal to] 15          0           3 (50.0)
  16 to 30                            4 (20.0)    5 (25.0)
  31 to 45                            6 (25.0)    8 (33.3)
  46 to 60                            5 (26.3)    8 (42.1)
  [greater than or equal to] 61       0           2 (66.7)

Table 2. Degree of recovery in relation to severity of hearing loss

                                               Complete     Moderate
Severity                         Patients,    recovery,     recovery,
of HL (dB)                           n          n (%)         n (%)

30 to 45                             7         7 (100)      0
46 to 90                            50        15 (30.0)     5 (10.0)
[greater than or equal to] 91       15         0            4 (25.7)

Severity                         recovery,   No recovery,
of HL (dB)                         n (%)        n (%)

30 to 45                          0            0
46 to 90                         14 (28.0)    16 (32.0)
[greater than or equal to] 91     1 (6.7)     10 (66.7)
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Author:Derekoylu, Levent
Publication:Ear, Nose and Throat Journal
Geographic Code:1USA
Date:Oct 1, 2005
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