A New Phase in the Treatment of Alzheimers Disease is Expected to Begin in 2009 with the Launch of Drugs That Slow the Progression of the Disease - Alzhemed and Flurizan.DUBLIN, Ireland -- Research and Markets (http://www.researchandmarkets.com/reports/c30185) has announced the addition of Alzheimers Disease - Beta Treatments on the Horizon to their offering. Alzheimers patients remain poorly treated and are growing in number. Currently, cholinesterase inhibitors cholinesterase inhibitor n. A drug, such as neostigmine, that restores myoneural function by inhibiting the biodegradation of acetylcholine. Also called acetylcholinesterase inhibitor. and the more recent NMDA-receptor antagonists antagonists, n muscles that counterbalance agonists during specific movements. opioid Neurology A pain-attenuating peptide that occurs naturally in the brain, which induces analgesia by mimicking endogenous opioids at opioid provide only moderate and temporary symptomatic symptomatic /symp·to·mat·ic/ (simp?to-mat´ik) 1. pertaining to or of the nature of a symptom. 2. indicative (of a particular disease or disorder). 3. benefit. By the end of the decade, however, drugs with the ability to slow the rate of disease progression are expected to be launched - most notably, the first beta-amyloid beta-amyloid A4, β—amyloid Neurology A 4 kD polypeptide encoded on chromosome 21 arising from altered processing of amyloid precursor protein, an integral membrane glycoprotein secreted as a truncated carboxyl-terminal molecule; BA forms plaques in the modulators. This report provides an overview of the epidemiology epidemiology, field of medicine concerned with the study of epidemics, outbreaks of disease that affect large numbers of people. Epidemiologists, using sophisticated statistical analyses, field investigations, and complex laboratory techniques, investigate the cause of Alzheimers disease across the seven major markets and its diagnosis and management. It includes an examination of the Alzheimers disease pipeline with clinical and commercial profiles of late-stage candidates. Seven market sales forecasts Sales forecast A key input to a firm's financial planning process. External sales forecasts are based on historical experience, statistical analysis, and consideration of various macroeconomic factors. , commercial potential and research/clinical/commercial assessment of late-stage products to 2014 are provided. The report includes insight and commentary from qualitative interviews with Alzheimers disease opinion leaders in the US, Europe and Japan The Alzheimers disease market is forecast to continue to expand significantly over the next ten years. Aided by growing elderly populations, successive product launches have seen global revenues grow at over 35% CAGR CAGR See: Compound Annual Growth Rate 200104. A new phase in the treatment of Alzheimers disease is expected to begin in 2009 with the launch of drugs that slow the progression of the disease - Alzhemed and Flurizan. Once launched, however, these drugs may not have long before further generations of disease modifying drugs arrive, pushing sales of Alzhemed and Flurizan into decline from 2013. Clinical trial design will be key to the success of many new products. Trial duration must be appropriate for the drugs mechanism of action. Furthermore, selection of individuals from Alzheimers disease subgroups or those more likely to get the disease, can lead to better efficacy demonstration and lower required recruitment numbers. Reasons to Purchase --Understand concerns over efficacy of currently available therapies and the impact of this on AChEI use --Identify potential patient segments in Alzheimers Disease for key late-stage compounds and rank future products --Assess the global sales forecasts of currently marketed products and evaluate the impact of generic galantamine galantamine /ga·lan·ta·mine/ (gah-lan´tah-men) a reversible competitive inhibitor of acetylcholinesterase used as the hydrobromide salt in the treatment of Alzheimer's disease. Companies mentioned: --Pfizer/Eisai --Johnson & Johnson --Novartis --Forest --Eli Lilly --Sanofi-Aventis --Axonyx -- Mindset mind·set or mind-set n. 1. A fixed mental attitude or disposition that predetermines a person's responses to and interpretations of situations. 2. An inclination or a habit. Topics covered include: --Patient Potential --Market Overview --Country Market Assessment --R&D Approach --Drug Pipeline Analysis --Beta-Amyloid Modulators - Late-Stage Pipeline Analysis & Forecasts --Acetylcholine Modulators - Late-Stage Pipeline Analysis and Forecasts --NMDA Modulators - Late-Stage Pipeline Analysis and Forecasts --Neuroprotectants - Late-Stage Pipeline Analysis and Forecasts --Other Drugs - Late-Stage Pipeline Analysis and Forecasts --Innovative Early-Stage Projects --Forecast Analysis --Commercial Impact and Lifecycle Management: Case Studies For more information visit http://www.researchandmarkets.com/reports/c30185 |
|
||||||||||||||

Printer friendly
Cite/link
Email
Feedback
Reader Opinion