30,000 Renal Transplants Were Performed in 2005, Increasing to 43,000 by 2015 (CAGR, 2005-15, 4%), Although the 'Organ Gap' May Widen Further.DUBLIN, Ireland -- Research and Markets (http://www.researchandmarkets.com/reports/c35650) has announced the addition of Kidney Transplantation Kidney Transplantation Definition Kidney transplantation is a surgical procedure to remove a healthy, functioning kidney from a living or brain-dead donor and implant it into a patient with non-functioning kidneys. - Switching to Calcineurin Inhibitor-Free Immunosuppression immunosuppression Suppression of immunity with drugs, usually to prevent rejection of an organ transplant. Its aim is to allow the recipient to accept the organ permanently with no unpleasant side effects. to their offering. In 2005, around 30,000 renal transplants were conducted in the seven major markets. In order to prevent the patient's immune system from rejecting the transplanted organ, daily immunosuppression therapy is a necessity for the lifetime of the graft with a base maintenance drug (cyclosporine cyclosporine /cy·clo·spor·ine/ (-spor´en) a cyclic peptide from an extract of soil fungi that selectively inhibits T cell function; used as an immunosuppressant to prevent rejection in organ transplant recipients and to treat severe , tacrolimus, sirolimus) combined with adjunctive therapies (azathioprine azathioprine: see metabolite. , mycophenolate mofetil, steroids). Scope of this title: Historical and recent trends in immunosuppressive therapy including current clinical practice and clinical advantages and side effects of treatments Organ supply, national donation rates, waiting lists and forecasts of the number of transplants and maintenance populations to 2015 Primary diagnosis, graft survival rates, reasons for late graft failure and risk factors associated with acute rejection Future market outlook including calcineurin inhibitor avoidance/withdrawal strategies Report Highlights 30,000 renal transplants were performed in 2005, increasing to 43,000 by 2015 (CAGR CAGR See: Compound Annual Growth Rate , 2005-15, 4%), although the "organ gap" may widen further as increasing morbidity, such as diabetes mellitus, drives demand. The number of patients with functioning kidney transplants will double to 428,000 by 2015, creating a large group of patients with unique and complex long-term medical care needs directly attributable to adverse effects of immunosuppressive drugs, including nephrotoxicity neph·ro·tox·ic·i·ty n. The quality or state of being toxic to kidney cells. nephrotoxicity(ne·fr , diabetes, hypertension, hyperlipidemia hyperlipidemia /hy·per·lip·id·emia/ (-lip?i-de´me-ah) elevated concentrations of any or all of the lipids in the plasma, including hypertriglyceridemia, hypercholesterolemia, etc. and vulnerability to infection. Although prevention of acute rejection remains a primary treatment goal, agents that do not impair long-term renal function are required. While results from sirolimus based calcineurin-inhibitor withdrawal regimens are inconclusive more promising results are emerging from use in the calcineurin-inhibitor avoidance or switching setting. Reasons to order your copy: Identify changing trends in immunosuppressive Immunosuppressive Any agent that suppresses the immune response of an individual. Mentioned in: Antirheumatic Drugs, Graft-vs.-Host Disease, Immunosuppressant Drugs immunosuppressive 1. pertaining to or inducing immunosuppression. 2. protocols Understand the most common treatment protocols in renal transplantation by patient type Quantify the future market size based on the number of transplants and renal maintenance populations Chapters are as follows:- Chapter 1 Executive summary Chapter 2 Market environment Chapter 3 Organ supply and demand Chapter 4 Kidney transplantation Chapter 5 Optimizing immunosuppression Chapter 6 Appendix For more information visit http://www.researchandmarkets.com/reports/c35650 Source: Datamonitor |
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