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2nd Annual Albert Szent-Gyorgyi Prize for Progress in Cancer Research Awarded to Webster K. Cavenee, Ph.D.


BETHESDA, Md. -- The National Foundation for Cancer Research The National Foundation for Cancer Research was founded in 1973 as a non-profit organization under U.S. tax code 501(c)(3). Over the past 30 years, NFCR has provided more than $200 million in support of discovery-oriented basic science cancer research and cancer prevention.  (NFCR) announced today that Webster K. Cavenee, Ph.D. has been awarded the 2nd Annual Albert Szent-Gyorgyi Prize for Progress in Cancer Research. Dr. Cavenee, Director of the Ludwig Institute for Cancer Research The Ludwig Institute for Cancer Research (LICR) is a global non-profit medical research institute that undertakes laboratory and clinical research into cancer, conducting and sponsoring its own early-phase clinical trials to investigate its discoveries.  and Distinguished Professor at the University of California, San Diego UCSD is consistently ranked among the top ten public universities for undergraduate education in the United States by U.S. News & World Report.[3] It is a Public Ivy. [1] For graduate studies, most of UCSD's Ph.D. , won the prize for his groundbreaking discoveries regarding the genetic mechanisms of predisposition to human cancer. Dr. Cavenee's research provided the first genetic evidence for the existence of tumor suppressor genes, one of the most influential breakthroughs in cancer research.

The annual Albert Szent-Gyorgyi Prize for Progress in Cancer Research was established to recognize outstanding scientific achievement in the war against cancer and to honor pioneering scientists who have made extraordinary contributions in the field of cancer research. The Prize is designed to draw attention to the continued need to support basic cancer research and the role that it plays in new cancer therapies. The Prize includes a $25,000 honorarium HONORARIUM. A recompense for services rendered. It is usually applied only to the recompense given to persons whose business is connected with science; as the fee paid to counsel.
     2.
.

"Dr. Cavenee is a pioneer in the truest sense of the word. His research on tumor suppressor genes has not only advanced our understanding of cancer, but it also has provided valuable insight in the role that hereditary predisposition plays into developing cancer," said Dr. Harold Dvorak of Beth Israel Deaconess Hospital and Chair of the Szent-Gyorgyi Prize Selection Committee.

"Dr. Cavenee's discoveries have helped to pave the way for researchers to better break down cancer's complicated molecular structures and understand the role that tumor suppressor genes play in cancer growth and development," said Dr. Sujuan Ba, Co-Chair of the Szent-Gyorgyi Prize Selection Committee and Chief Scientific Officer of NFCR.

Dr. Cavenee's original research seeking to define the genetic lesions in retinoblastoma Retinoblastoma Definition

Retinoblastoma is a malignant tumor of the retina that occurs predominantly in young children.
Description

The eye has three layers, the sclera, the choroid, and the retina.
 led to the first hard experimental evidence for the existence of tumor suppressor genes in humans. This breakthrough confirmed the "two-hit hypothesis," fundamentally altering the way scientists think about the onset of cancer and its progression. Today, mutations of tumor suppressor genes have been identified in more than half of all tumors, including those of muscle, melanocytes Melanocytes
Skin cells derived from the neural crest that produce the protein pigment melanin.

Mentioned in: Malignant Melanoma, Skin Pigmentation Disorders

melanocytes
, kidney, prostate, and breast. Novel gene therapies to reverse gene mutations or their effects in cancer cells hold promise as cancer treatment strategies which could be of benefit to cancer patients.

Today Dr. Cavenee is the Director of the Ludwig Institute for Cancer Research based at the University of California, San Diego and a Professor of Medicine in the cancer biology program at UCSD. He is a Fellow of the National Foundation for Cancer Research and has won many honors, including the Charles S. Mott Prize The $250,000 Charles S. Mott Prize is awarded annually by the General Motors Cancer Research Foundation. The Mott Prize is one of a trio scientific prizes entirely devoted to cancer research (the other prizes being the Charles F. Kettering Prize and the Alfred P. Sloane Prize).  of the General Motors Cancer Research Foundation. He is a member of the National Academy of Sciences, a Past-President of the American Association for Cancer Research Wikipedia is not the place for advertisement or self-advertising.

The American Association for Cancer Research (AACR) is an organization based in Philadelphia, Pennsylvania, that focuses on all aspects of cancer research including basic, clinical and translational
, a Fellow of the American Academy of Microbiology, and serves on the editorial boards of several journals. He has also served on the Board of both the Scientific Counselors of the National Cancer Institute and the National Institute of Environmental Health Sciences The National Institute of Environmental Health Sciences (NIEHS) is one of 27 Institutes and Centers of the National Institutes of Health (NIH),which is a component of the Department of Health and Human Services (DHHS). The Director of the NIEHS is Dr. David A. Schwartz. . Dr. Cavenee received his doctorate from the University of Kansas The University of Kansas (often referred to as KU or just Kansas) is an institution of higher learning in Lawrence, Kansas. The main campus resides atop Mount Oread.  School of Medicine.

"The Albert Szent-Gyorgyi Prize for Progress in Cancer Research means a great deal to the cancer research field and I am humbled to have been selected by my peers to receive it. It is my hope that the discoveries I am being recognized for will have significant long-term impact on those patients who suffer from cancer around the world. That is the real prize," said Dr. Cavenee. "The support of the National Foundation for Cancer Research over the years both for this Prize and for basic cancer research has been a vital part of many significant research discoveries."

The Albert Szent-Gyorgyi Prize for Progress in Cancer Research was established by the National Foundation for Cancer Research in honor of its co-founder, Dr. Albert Szent-Gyorgyi, recipient of the 1937 Nobel Prize for Physiology and Medicine for his study on Vitamin C and cell respiration. Dr. Szent-Gyorgyi was a leading advocate for developing resources to provide scientists with the financial support necessary to pursue novel cancer research ideas. In 1973, he changed the face of cancer research funding by co-founding the National Foundation for Cancer Research. Any scientist or individual may be nominated for the annual award by their peers and the winner is selected by a prize selection committee comprised of academic, scientific, business and non-profit leaders highly qualified to review and select the Prize winner.

The 2nd Annual Albert Szent-Gyorgyi Prize selection committee was chaired by the inaugural prize recipient: Harold Dvorak, M.D. Committee members were Sujuan Ba, Ph.D.; Yi Michael Wang, M.D., Ph.D., National Foundation for Cancer Research; Dennis Carson, M.D., University of California, San Diego; Stanley Cohen, M.D., Stanford University; Carlo Croce, M.D., Ohio State University Ohio State University, main campus at Columbus; land-grant and state supported; coeducational; chartered 1870, opened 1873 as Ohio Agricultural and Mechanical College, renamed 1878. There are also campuses at Lima, Mansfield, Marion, and Newark. ; Richard Gaynor, M.D., Eli Lilly; Rakesh Jain, Ph.D. Massachusetts General Hospital Massachusetts General Hospital Health care The major teaching hospital for Harvard Medical School, widely regarded as one of the best health care centers in the world ; Thea Tlsty, Ph.D., University of California, San Francisco Coordinates:  ; Daniel Von Hoff, M.D., FACS FACS Fellow of the American College of Surgeons.

FACS
abbr.
Fellow of the American College of Surgeons



FACS

fluorescence-activated cell sorter.
, TGen and Arizona Cancer Center; and Bruce Zetter, Ph.D., Children's Hospital Boston Children's Hospital Boston is a children's hospital located in the Longwood Medical and Academic Area of Boston, Massachusetts. Located at 300 Longwood Avenue, Children's is adjacent both to its teaching affiliate, Harvard Medical School, and to Dana-Farber Cancer Institute. .

About the National Foundation for Cancer Research

The National Foundation for Cancer Research (NFCR) was founded in 1973 to support cancer research and public education relating to earlier prevention, better diagnosis, new and more effective treatments, and ultimately cures for all types of cancer. NFCR promotes and facilitates collaboration among scientists to accelerate the pace of discovery from bench to bedside.

To date, NFCR has provided over $230 million in support of discovery-oriented basic research focused on understanding how and why cells become cancerous and on cancer prevention. NFCR's scientists are discovering cancer's molecular mysteries and translating these discoveries into therapies that hold the hope for curing cancer. NFCR is about Research for a Cure--cures for all types of cancer.
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Date:Jan 17, 2007
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