25th Anniversary LTS LOHMANN Therapie-Systeme AG.ANDERNACH, Germany & WEST CALDWELL, N.J. -- LTS LTS 1 Latent tetany syndrome, see there 2. Low-threshold spike–neurology LOHMANN Therapie-Systeme AG, the leading developer and manufacturer of transdermal, topical and oral systems with facilities in Andernach, Germany and West Caldwell, New Jersey, celebrates its 25th anniversary. LTS' 2008 turnover was over [euro] 200 million in its own manufacturing, with its products - sold by the world's leading pharmaceutical and consumer companies - selling over [euro]20 Billion. Development of transdermal therapeutic systems started in 1979 at Lohmann in Neuwied, Germany. The first nitroglycerin nitroglycerin (nī'trōglĭs`ərĭn), C3H5N3O9, colorless, oily, highly explosive liquid. It is the nitric acid triester of glycerol and is more correctly called glycerol trinitrate. matrix patch for the treatment of heart disease was introduced in 1983 in Europe, followed by the US. Shortly afterwards, LTS was created and research and manufacturing facilities established in Germany and the US. In 1999, LTS became an independent corporation now primarily owned by three well funded stockholders. LTS products include the world's first nicotine patch nicotine patch Nicotine transdermal delivery system Substance abuse A device used in smoking cessation Side effects Transient burning, itching–50%, erythema–14%; contact hypersensitivity–2.4%. See Nicotine replacement therapy. , which created a new class of treatment for smoking cessation smoking cessation Public health Temporary or permanent halting of habitual cigarette smoking; withdrawal therapies–eg, hypnosis, psychotherapy, group counseling, exposing smokers to Pts with terminal lung CA and nicotine chewing gum are often ineffective. and enjoys annual sales of [euro]350 million; the first estradiol matrix system - hormone replacement therapy Hormone Replacement Therapy Definition Hormone replacement therapy (HRT) is the use of synthetic or natural female hormones to make up for the decline or lack of natural hormones produced in a woman's body. for the treatment of menopause; A birth control patch; buprenorphine Transtec[TM], Norspan[TM], Butrans[TM] patches for the treatment of chronic pain; a rivastigmine patch for the treatment of Alzheimer's disease Alzheimer's disease (ăls`hī'mərz, ôls–), degenerative disease of nerve cells in the cerebral cortex that leads to atrophy of the brain and senile dementia. , with 2008 sales by Novartis of over $800 million, and a rotigotine patch for Parkinson's disease Parkinson's disease or Parkinsonism, degenerative brain disorder first described by the English surgeon James Parkinson in 1817. When there is no known cause, the disease usually appears after age 40 and is referred to as Parkinson's disease. and Restless Legs Syndrome Restless Legs Syndrome Definition Restless legs syndrome (RLS) is characterized by unpleasant sensations in the limbs, usually the legs, that occur at rest or before sleep and are relieved by activity such as walking. - the first drug in the world developed initially in a patch formulation and the only patch on the market for the treatment of Parkinson's. In the oral care market, LTS' pioneering work with thin films in New Jersey led to the introduction of Listerine[R] Pocketpaks[R], enjoying a dominant market position in North America with over 1 Billion strips manufactured in the first three years. Lately, several wafer products including Listerine Whitening Strips[R] were also introduced in the US. The company's leading technology development position is supported by over 5,000 patents issued over the years. In the late 1990s, LTS acquired a clinical research organization which now, under the name 'CRS Clinical Research Services', carries out clinical trials in several locations in Germany, and will shortly expand internationally. Dr. H. Rainer Hoffmann, Chairman of LTS, has been with LTS from the beginning in the first research lab and has led the company since its spin-off from Lohmann 25 years ago, to its present position. |
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