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2009 H1N1 vaccine shows promise in children.


Byline: ANI

Washington, Sept 22 (ANI): The preliminary trials testing the efficacy of 2009 H1N1 vaccine in kids aged of 10 to 17 has shown promising results.

The researchers found that a single 15-microgram dose of a non-adjuvanted 2009 H1N1 influenza vaccine influenza vaccine Flu vaccine A vaccine recommended for those at high risk for serious complications from influenza: > age 65; Pts with chronic diseases of heart, lung or kidneys, DM, immunosuppression, severe anemia, nursing home and other chronic-care  - the same dose that is in the seasonal flu vaccine


    The flu vaccine is a vaccine to protect against the highly variable influenza virus.

    The annual flu kills an estimated 36,000 people in the United States.
     - generates an immune response immune response
    n.
    An integrated bodily response to an antigen, especially one mediated by lymphocytes and involving recognition of antigens by specific antibodies or previously sensitized lymphocytes.
     that is expected to be protective against 2009 H1N1 influenza virus influenza virus
    n.
    Any of three viruses of the genus Influenzavirus designated type A, type B, and type C, that cause influenza and influenzalike infections.
     in the majority kids within 8 to 10 days after vaccination.

    "This is very encouraging news," said NIAID NIAID National Institute of Allergy and Infectious Diseases.  Director Dr Anthony S. Fauci.

    "As we had hoped, responses to the 2009 H1N1 influenza vaccine are very similar to what we see with routinely used seasonal influenza vaccines made in the same way.

    "It seems likely that the H1N1 flu vaccine will require just one 15-microgram dose for children 10 to 17 years of age. The 2009 H1N1 influenza virus is causing widespread infections among children, so these are welcome results," he added.

    The ongoing trial, sponsored by National Institute of Allergy and Infectious Diseases, is assessing the safety and immune responses to one and two doses of either 15 micrograms or 30 micrograms of vaccine.

    The study showed that immune responses were strongest among the oldest children, those 10 to 17 years old after first vaccination.

    In a group of 25 children, a strong immune response was seen in 76 percent who received one 15-microgram dose of vaccine.

    In the youngest group, 20 children between 6 months to 35 months old, a single 15-microgram dose of vaccine produced a strong immune response in 25 percent of recipients.

    "These results are not unexpected and are both similar to what is seen with seasonal influenza vaccines and consistent with what we and our colleagues at the Food and Drug Administration anticipated," said Dr. Fauci.

    The vaccine being tested in this trial is manufactured by Sanofi Pasteur in Swiftwater, Pa., in the same manner as its licensed seasonal vaccine.

    Like inactivated inactivated

    rendered inactive; the activity is destroyed.


    inactivated viruses
    treated so that they are no longer able to produce evidence of growth or damaging effect on tissue.
     seasonal influenza vaccines, the vaccine contains a purified part of a killed virus and cannot cause flu. (ANI)

    Copyright 2009 Asian News International The Asian News International (ANI) agency provides multimedia news to China and 50 bureaus in India. It covers virtually all of South Asia since its foundation and presently claims, on its official website, to be the leading South Asia-wide news agency.  (ANI) - All Rights Reserved.

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    No portion of this article can be reproduced without the express written permission from the copyright holder.
    Copyright 2009 Gale, Cengage Learning. All rights reserved.

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    Publication:Asian News International
    Date:Sep 22, 2009
    Words:360
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