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20/20 Launches Innovative Bio-Terrorism Field Test for 1st Responders.


Business Editors/Health & Medical Writers

ROCKVILLE, Md.--(BUSINESS WIRE)--Feb. 11, 2003

Five Minute Protein Test Screens for Ricin ricin /ri·cin/ (ri´sin) a phytotoxin in the seeds of the castor oil plant (Ricinus communis), used in the synthesis of immunotoxins.

ri·cin
n.
, Anthrax anthrax (ăn`thrăks), acute infectious disease of animals that can be secondarily transmitted to humans. It is caused by a bacterium (Bacillus anthracis  &

Other Terror Agents Ruling Out More than

80% of Safe Substances

20/20 GeneSystems, Inc. (20/20), a biotechnology company, today announced the launch of a new product to help first responders screen suspicious powders for bioterrorism agents.

The BioCheck(TM) Powder Screening Kit works by quickly identifying the presence or absence of protein, a biomolecule biomolecule /bio·mol·e·cule/ (-mol´e-kul) a molecule produced by living cells, e.g., a protein, carbohydrate, lipid, or nucleic acid.

biomolecule

a molecule produced by living cells, e.g.
 found in all living materials. It therefore provides a rapid screen for the possible presence of multiple bioterrorism agents such as anthrax and ricin toxin Noun 1. ricin toxin - a toxic protein extracted from castor beans; used as a chemical reagent; can be used as a bioweapon; "one milligram of ricin can kill an adult"
ricin
, while ruling out most of the ordinary substances that citizens have frequently feared to be possible weapons of mass destruction Weapons that are capable of a high order of destruction and/or of being used in such a manner as to destroy large numbers of people. Weapons of mass destruction can be high explosives or nuclear, biological, chemical, and radiological weapons, but exclude the means of transporting or  (WMDs).

The product requires no instruments and helps first responders determine in five minutes or less whether testing for one or more specific pathogens or toxins is warranted. 20/20's kits are now being sold to fire departments and public safety personnel worldwide for under $25.

Demand for this product is expected to increase in light of announcements last week by senior U.S. law enforcement and health officials about the possible use of ricin toxin, a highly poisonous plant poisonous plant, any plant possessing a property injurious to man or animal. Plants may be poisonous to the touch (e.g., poison ivy, poison sumac), or orally toxic (e.g., poison hemlock, deadly amanita). Many poisonous plants are of great value medicinally, e.g.  protein, as a terrorist weapon. According to Attorney General John D. Ashcroft, U.S. officials were "particularly concerned" about the recent finding of ricin toxin manufacturing equipment in a London apartment of a group associated with al Qaeda that may have operatives the United States.

At the height of the anthrax mailings in late 2001, scientists from 20/20 collaborated with fire officials and HAZMAT crews from Montgomery County Maryland who at the time were overwhelmed with hundreds of "suspicious powder" 911 calls that turned out to be ordinary substances like sugar, drywall dust, cornstarch cornstarch, material made by pulverizing the ground, dried residue of corn grains after preparatory soaking and the removal of the embryo and the outer covering. It is used as laundry starch, in sizing paper, in making adhesives, and in cooking. , etc.

"It became clear from these meetings that there was an urgent need for a primary screening test to help first responders in the field separate ordinary powders from those needing an array of specific agent testing. It was simply not practical to subject every sample to 48 hour laboratory testing nor to conduct a half-dozen specific agent field tests each time a powder was found," said Liz Marcus, 20/20's manager for the product.

For over a year, 20/20 has developed, optimized and refined the BioCheck test kit to make it robust, reliable and readily useable by first responders in a variety of field conditions. Early product evaluation was done by members of the Montgomery County Fire & Rescue Service, who continue to use the product in their investigations.

It was evaluated more than 50 times by HAZMAT teams in the Washington D.C. Metropolitan area in response to actual 911 calls resulting from suspicious powders in post offices, on subways, and at organizations such as the IMF IMF

See: International Monetary Fund


IMF

See International Monetary Fund (IMF).
.

The kit was effective in ruling out more than 80% of substances that led citizens to call 911 including cornstarch, drywall dust and powdered sugar thereby limiting the number of samples requiring more time consuming and costly specific agent testing.

The product is now a primary screening test used by HAZMAT teams in the District of Columbia District of Columbia, federal district (2000 pop. 572,059, a 5.7% decrease in population since the 1990 census), 69 sq mi (179 sq km), on the east bank of the Potomac River, coextensive with the city of Washington, D.C. (the capital of the United States).  and has been incorporated into that department's standard operating procedures standard operating procedure Medtalk A technique, method or therapy performed 'by the book,' using a standard protocol meeting internally or externally defined criteria; a formal, written procedure that describes how specific lab operations are to be performed.  (SOPs). About a dozen other departments and agencies throughout the U.S. and overseas are now evaluated or using the product.

"The BioCheck Powder Screen Kit is another presumptive pre·sump·tive  
adj.
1. Providing a reasonable basis for belief or acceptance.

2. Founded on probability or presumption.



pre·sump
 tool that our Hazardous Incident Response Team and Bomb Squad can use at the scene of suspicious powder calls. Though this and other tools we use are not confirmatory, they do serve to help us get a better indication of what we may have. We follow up with laboratory analysis as part of our response protocol," said Ted Jarboe, Deputy Chief of the Division of Fire and Rescue Services, Montgomery County Maryland. Chief Jarboe is a member of the Terrorism Committee of the International Association of Fire Chiefs The International Association of Fire Chiefs (IAFC) is a network of more than 12,000 chief fire and emergency officers.[1] The Association was established in 1873.[1] The Executive Director is Mark W. Light. .

In addition to field testing, the BioCheck Powder Screening Kit has been extensively tested using an anthrax simulant by an internationally recognized independent testing laboratory and found to offer comparable sensitivity to other kits on the market designed to specifically test for anthrax. The product has also been tested with actual anthrax bacteria by the Metropolitan Health Research Center in Tokyo, Japan. In ten out of ten tests, anthrax was detected using the 20/20 product.

20/20 GeneSystems plans to announce one or more major distribution relationships in the next few weeks. In the meantime Adv. 1. in the meantime - during the intervening time; "meanwhile I will not think about the problem"; "meantime he was attentive to his other interests"; "in the meantime the police were notified"
meantime, meanwhile
 fire departments and public safety professionals can order the product from 20/20 GeneSystems. For more information, call 240/453-6339 or visit the website at www.2020gene.com.

About 20/20 GeneSystems

20/20 GeneSystems was founded in 2000 and is based in Rockville, Maryland. The company develops and markets innovative protein identification products for life science research, diagnostic and homeland security markets.
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Publication:Business Wire
Geographic Code:1USA
Date:Feb 11, 2003
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