* Titan studies oral effect of gallium maltolate to treat prostate cancer.Titan Pharmaceuticals Inc., South San Francisco South San Francisco, city (1990 pop. 54,312), San Mateo co., W Calif.; inc. 1908. South San Francisco has several industrial parks; its manufactures include medical supplies and equipment, foods, paint, paper products, consumer goods, and clothing. , CA, has begun Phase II clinical testing of gallium maltolate in patients with metastatic Metastatic The term used to describe a secondary cancer, or one that has spread from one area of the body to another. Mentioned in: Coagulation Disorders metastatic pertaining to or of the nature of a metastasis. prostate cancer and refractory multiple myeloma, the company has announced. The randomized ran·dom·ize tr.v. ran·dom·ized, ran·dom·iz·ing, ran·dom·iz·es To make random in arrangement, especially in order to control the variables in an experiment. , controlled study will enroll 58 patients at several centers. It is designed to assess the safety and preliminary efficacy of gallium maltolate, an orally active formulation of gallium. Gallium is a semimetallic Sem`i`me`tal´lic a. 1. (Chem.) Of or pertaining to a semimetal; possessing metallic properties in an inferior degree; resembling metal. element that inhibits ribonucleotide reductase, an enzyme that promotes tumor growth, according to Titan. The element also is known to concentrate in malignant tumors and at sites of infections. It also appears to enhance calcium deposition, which makes bones more resistant to the degradation caused by cancer metastasis. |
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