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'Holy grail' drug may make scars a thing of the past.


Byline: ANI

London, Apr 10 (ANI): A new healing drug can reduce scarring after surgery or injury, say UK researchers.

At the site of the wound before and after an incision incision /in·ci·sion/ (in-sizh´un)
1. a cut or a wound made by cutting with a sharp instrument.incis´ional

2. the act of cutting.


in·ci·sion
n.
1.
, the drug, a synthetic cell- signalling agent, is injected under the skin.

To reach the conclusion, researchers conducted three trials of the treatment on groups of volunteers who willingly suffered centimetre-wide puncture wounds puncture wound
n.
A wound that is deeper than it is wide, produced by a narrow pointed object.
 in their arms. The incisions were deep enough to penetrate through the skin to underlying muscle, reports The Scotsman.

Different amount of doses of the drug avotermin, an artificial form of TGFbeta3, were injected at the wound site both before and 24 hours after the incisions were made.

Scarring appearance was assessed using a 100-point scale. Trial participants were split into two groups, one receiving the anti-scarring therapy and the other a dummy treatment.

In two trials, lower doses of the drug improved scarring appearance by up to eight points after 12 months. A third trial using higher doses resulted in improvements of as much as 64 points on the visual assessment scale.

Professor Mark Ferguson
This article is about the actor. For the television news presenter see Mark Ferguson (television presenter).


Mark Ferguson (born 28 February, 1961 in Sydney, New South Wales, Australia) is an New Zealand-based Australian actor and television
, from the University of Manchester The University of Manchester is a university located in Manchester, England. With over 40,000 students studying 500 academic programmes, more than 10,000 staff and an annual income of nearly £600 million it is the largest single-site University in the United Kingdom and receives , and colleagues wrote in The Lancet medical journal: "We detected substantial differences in collagen collagen (kŏl`əjən), any of a group of proteins found in skin, ligaments, tendons, bone and cartilage, and other connective tissue. Cells called fibroblasts form the various fibers in connective tissue in the body.  organisation in some participants, with avotermin-treated scars more closely resembling the basket-weave pattern of normal skin." (ANI)

Copyright 2009 Asian News International The Asian News International (ANI) agency provides multimedia news to China and 50 bureaus in India. It covers virtually all of South Asia since its foundation and presently claims, on its official website, to be the leading South Asia-wide news agency.  (ANI) - All Rights Reserved.

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Publication:Asian News International
Date:Apr 10, 2009
Words:233
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