`Protein Profiling: Quantitative Mass Spectrometry for Expression Analysis' Instructional Webcast on October 27, 2004.

LARCHMONT, N.Y. -- A virtual seminar on "Protein Profiling: Quantitative Mass Spectrometry for Expression Analysis," presented by Genetic Engineering News (www.GENseminars.com), will take place on Wed., October 27, 2004, at 12 pm EDT (NY daylight savings time). This live webcast will present the latest mass spec data and technologies relating to expression and characterization of proteins for development of therapeutics and for biological understanding.

Presenting will be Christopher Colangelo, Ph.D., Director of Protein Profiling at the W.M. Keck Foundation Biotechnology Resource Laboratory, of Yale University. Dr. Colangelo completed his doctoral research in chemistry at the University of Georgia and holds patents in nucleic acid sequencing and amplification. He thus offers attendees of this GEN virtual seminar access to a high level of chemistry and mass spec knowledge relevant to therapeutics development. The Keck Laboratory has been hailed by the NIH as one of the "best facilities of its kind in the nation" for providing state-of-the-art proteomics and genomics technologies to researchers within Yale and beyond.

Jennifer Krone, Ph.D., Senior Field Applications Specialist for Proteomics at Applied Biosystems, will moderate the event. Dr. Krone received her Ph.D. in analytical chemistry from Arizona State University, where she studied MALDI mass spectrometry, and the use of immunoassays and surface plasmon resonance-mass spectrometry in biomolecular characterization. She subsequently served as partner at Intrinsic Bioprobes, and director of analytical chemistry, then vp of lab services, at Lovelace Respiratory Research Institute, before joining industry as a technical sales and marketing specialist--first at Proteometrics (acquired by Genomic Solutions), and currently at Applied Biosystems. Dr. Krone will thus bring an expert perspective drawing on a strong analytical chemistry background, combined with intimate knowledge of the particular mass spec needs of the bioindustry for drug discovery research.

This 90-minute virtual seminar will present:

--New data and novel proteomic mass spectrometry technologies for simultaneous identification and quantification of proteins within biological samples

--Means of overcoming limitations of DNA microarray techniques for expression analysis

--Advances toward quantitative, comprehensive characterization of all cellular components and associated activity in a given biological system

--Monitoring of cellular changes associated with disease states and external influences for complex proteomic analyses

--Implications of broadened knowledge of expression and protein characterization for biological systems and therapeutics development

"Much of medicine in the 21st century will be about proteomics and the use of proteins as therapeutic options," says John Sterling, editor in chief of Genetic Engineering News. "Mass spectrometry is a key technology for characterizing proteins, and this seminar will present up-to-date methods to overcome roadblocks in proteomics projects at both research and commercial levels."

Registrations for "Protein Profiling: Quantitative Mass Spectrometry for Expression Analysis" are limited to ensure interactive participation. To register online, and for further information, visit www.GENseminars.com.

Genetic Engineering News (www.genengnews.com) is the most widely read publication in the biotechnology industry and the only high-frequency publication focused on international bioindustry news. Established in 1981, GEN is also the oldest biotechnology publication, having covered the industry since its inception. GEN is published by Mary Ann Liebert, Inc., a privately held, fully integrated media company known for developing authoritative peer-reviewed journals in cutting-edge areas of bioscience and medicine, engineering, law, and business.