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[0] Gene Tec's Gene Amplification Method Licensed by Applied Biosystems.


Business Editors, Health/Medical Writers

BIOWIRE2K

DURHAM, N.C.--(BW HealthWire)--Aug. 9, 2000

Gene Tec Corporation, Durham, NC, granted Applied Biosystems Group (NYSE NYSE

See: New York Stock Exchange
:PEB PEB Physical Evaluation Board
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), a PE Corporation business, Foster City, Ca., a non-exclusive license to its patented method of amplifying nucleic acid targets directly in cells and viruses.

The method immobilizes biological specimens by drying them onto solid or porous supports, such as microscope slides or membranes, to which reagents are added for direct amplification. PE Biosystems's license applies only for use of Gene Tec's method with polymerase chain reaction polymerase chain reaction (pŏl`ĭmərās') (PCR), laboratory process in which a particular DNA segment from a mixture of DNA chains is rapidly replicated, producing a large, readily analyzed sample of a piece of DNA; the process is , or PCR PCR polymerase chain reaction.

PCR
abbr.
polymerase chain reaction


Polymerase chain reaction (PCR) 
, patents that they license from Hoffmann LaRoche. PE Biosystems agreed to pay Gene Tec royalties for the kits and instruments it sells for use with in situ PCR.

U. S. Pat. No. 6,103,192 will issue to Gene Tec on August 15, 2000. The patent discloses Gene Match(TM) devices that are now available for single, direct PCR reactions without any nucleic acid preparation. Analysis of both RNA RNA: see nucleic acid.
RNA
 in full ribonucleic acid

One of the two main types of nucleic acid (the other being DNA), which functions in cellular protein synthesis in all living cells and replaces DNA as the carrier of genetic
 and DNA DNA: see nucleic acid.
DNA
 or deoxyribonucleic acid

One of two types of nucleic acid (the other is RNA); a complex organic compound found in all living cells and many viruses. It is the chemical substance of genes.
 in a single reaction is possible from minute, liquid or solid, tissue specimens. Gene Tec's Gene Flow(TM) chambers for hybridizing and washing glass slide microarrays are another patented technology coming out soon. The Gene Flow(TM) chamber manages flow of microfluidic volumes of probe and reagents to microarrays, accomplished either by manual pipetting or adapted for robotic liquid handling workstations.

Parties wanting more information about Gene Tec's innovative devices for DNA analyses, purchasing products or licensing technologies listed on http://www.ncbiotech.org/genetec.htm may contact Dr. Marilyn Stapleton at Gene Tec Corporation, 919-493-2022 or by fax, 919-419-1238.
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Publication:Business Wire
Date:Aug 9, 2000
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