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'Healthy' fat could lead to bowel disease.


Byline: ANI

Washington, July 24 (ANI): Consuming too much of polyunsaturated fat could lead to inflammatory bowel disease inflammatory bowel disease
n. Abbr. IBD
Any of several incurable and debilitating diseases of the gastrointestinal tract characterized by inflammation and obstruction of parts of the intestine.
, according to a new study.

Scientists believe that a high intake of linoleic acid may be implicated im·pli·cate  
tr.v. im·pli·cat·ed, im·pli·cat·ing, im·pli·cates
1. To involve or connect intimately or incriminatingly: evidence that implicates others in the plot.

2.
 in a third of ulcerative colitis cases.

Linoleic acid is a naturally occurring essential fatty acid
    Essential fatty acids, or EFAs, are fatty acids that cannot be constructed within an organism from other components (generally all references are to humans) by any known chemical pathways; and therefore must be obtained from the diet.
    , present in a variety of foods, including the oils of seeds and nuts, such as sunflower, safflower safflower, Eurasian thistlelike herb (Carthamus tinctorius) of the family Asteraceae (aster family). Safflower, or false saffron, has long been cultivated in S Asia and Egypt for food and medicine and as a costly but inferior substitute for the true saffron , soya, corn seeds or walnut oils.

    The findings are based of the dietary habits of more than 200,000 people.

    However, researchers also found that a diet rich in another type of fat, omega 3 fatty acid found in oily fish such as salmon and herring, reduced the likelihood of developing ulcerative colitis by 77 percent.

    The research team said that that there is a plausible biological mechanism that could explain why linoleic acid is linked with this bowel condition.

    Once in the body, linoleic acid is converted to arachidonic acid, which is a component of the cell membranes in the bowel.

    Arachidonic acid can then be converted into various inflammatory chemicals, high levels of which have been found in the bowel tissue of patients with ulcerative colitis.

    In all, 126 of the people in the study developed ulcerative colitis after an average period of four years.

    After taking into account other factors likely to influence the results, including smoking, age, total energy intake, and use of aspirin, those whose diets included the most linoleic acid were more than twice times as likely to develop the condition as those whose diets contained the least.

    "There are no dietary modifications of benefit in patients with ulcerative colitis, although, based on this study's findings, a diet low in linoleic acid may merit investigation," the BBC BBC
     in full British Broadcasting Corp.

    Publicly financed broadcasting system in Britain. A private company at its founding in 1922, it was replaced by a public corporation under royal charter in 1927.
     quoted lead author Dr Andrew Hart of the University of East Anglia “UEA” redirects here. For other uses, see UEA (disambiguation).
    Academically, it is one of the most successful universities founded in the 1960s, consistently ranking amongst Britain's top higher education institutions; 19th in the Sunday Times University League Table 2006
    , Norwich, as saying.

    The study has been published in the online journal Gut. (ANI)

    Copyright 2009 Asian News International The Asian News International (ANI) agency provides multimedia news to China and 50 bureaus in India. It covers virtually all of South Asia since its foundation and presently claims, on its official website, to be the leading South Asia-wide news agency.  (ANI) - All Rights Reserved.

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    COPYRIGHT 2009 Al Bawaba (Middle East) Ltd.
    No portion of this article can be reproduced without the express written permission from the copyright holder.
    Copyright 2009 Gale, Cengage Learning. All rights reserved.

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    Publication:Asian News International
    Date:Jul 24, 2009
    Words:334
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