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"SPORT" Study Confirms Positive Outcomes for Older Americans Having Spinal Fusion Surgery.


MINNEAPOLIS -- Medtronic, Inc. (NYSE NYSE

See: New York Stock Exchange
:MDT MDT
abbr.
Mountain Daylight Time


MDT (in the US and Canada) Mountain Daylight Time

MDT n abbr (US) (= mountain daylight time) →
) announced today it is pleased to see the recent study data showing Medicare patients suffering from degenerative spondylolisthesis spondylolisthesis /spon·dy·lo·lis·the·sis/ (-lis´the-sis) forward displacement of a vertebra over a lower segment, usually of the fourth or fifth lumbar vertebra due to a developmental defect in the pars interarticularis.  with spinal stenosis showed substantially greater improvement when treated surgically versus non-surgically. The results were part of the Spine Patient Outcomes Research Trial (SPORT), a study conducted at 11 sites across the U.S. and sponsored by the National Institutes of Health.

Results of this five year, multi-center study were published this week in the New England Journal of Medicine The New England Journal of Medicine (New Engl J Med or NEJM) is an English-language peer-reviewed medical journal published by the Massachusetts Medical Society. It is one of the most popular and widely-read peer-reviewed general medical journals in the world.  (NEJM NEJM New England Journal of Medicine ) showing that spinal fusion surgery benefited Medicare-aged patients suffering from degenerative spondylolisthesis with spinal stenosis. Earlier results, also establishing the success of spinal surgery involving middle-aged patients with intervertebral intervertebral /in·ter·ver·te·bral/ (-ver´te-bral) situated between two contiguous vertebrae; see under disk.

in·ter·ver·te·bral
adj.
Located between vertebrae.
 disc herniations, were published in 2006.

According to the article in the NEJM, the $13.5 million study showed that Medicare patients suffering from degenerative spondylolisthesis with spinal stenosis treated surgically showed substantially greater improvement in pain and function scores than patients who were treated non-surgically. While both the surgical and non-surgical patients showed improvement, the non-surgical patients showed only a moderate improvement while the surgical patients showed a substantial improvement.

SPORT was designed to compare three different indications using either surgery or non-operative care for patients with intervertebral disc herniation herniation /her·ni·a·tion/ (her?ne-a´shun) abnormal protrusion of an organ or other body structure through a defect or natural opening in a covering, membrane, muscle, or bone. , spinal stenosis and degenerative spondylolisthesis. The NEJM article follows an article on SPORT published in November 2006 in the Journal of the American Medical Association JAMA: The Journal of the American Medical Association is an international peer-reviewed general medical journal, published 48 times per year by the American Medical Association. JAMA is the most widely circulated medical journal in the world.  (JAMA JAMA
abbr.
Journal of the American Medical Association
), which reported that younger patients (average age 42) who had surgery fared better than non-surgical patients when it came to treating disc herniation.

Overall, 607 patients were enrolled in the study of degenerative spondylolisthesis with spinal stenosis. Of these patients, 304 were in the randomized ran·dom·ize  
tr.v. ran·dom·ized, ran·dom·iz·ing, ran·dom·iz·es
To make random in arrangement, especially in order to control the variables in an experiment.
 study population group (cohort), while 303 were in the observational cohort. The average age of these patients was 66 years.

In a series of patient self-assessment questionnaires, surgical patients showed statistically significant improvements in bodily pain, function and disability measurements over patients who underwent non-surgical options.

"As a surgeon participating in the study, I was pleased to see the results that confirm spinal fusion surgery is superior to non-surgical treatment in relieving symptoms and improving function for many older patients," said Jeffrey Goldstein, M.D., an orthopedic surgeon at New York University New York University, mainly in New York City; coeducational; chartered 1831, opened 1832 as the Univ. of the City of New York, renamed 1896. It comprises 13 schools and colleges, maintaining 4 main centers (including the Medical Center) in the city, as well as the  Hospital for Joint Diseases. "When other treatments fail, modern spinal surgery is a great option for patients suffering with back and leg pain."

Information on herniated disc treatments, patient testimonials and spinal surgery options can be found at www.back.com and www.insidespine.com.

About Medtronic's Spinal Business

Medtronic's spinal business, based in Memphis, Tenn., is the global leader in today's spine market and is committed to advancing the treatment of spinal conditions. Medtronic's spinal business collaborates with world-renowned surgeons, researchers and innovative partners to offer state-of-the-art products and technologies for neurological, orthopedic, dental and spinal conditions. Medtronic is committed to developing affordable, minimally invasive procedures that provide lifestyle friendly surgical therapies. More information about the company and its spinal treatments can be found at www.medtronicspinal.com and its patient-education Web sites, www.back.com, www.iscoliosis.com, www.maturespine.com and www.necksurgery.com.

About Medtronic

Medtronic, Inc. (www.medtronic.com), headquartered in Minneapolis, is the global leader in medical technology - alleviating pain, restoring health, and extending life for millions of people around the world.

Any forward-looking statements are subject to risks and uncertainties such as those described in Medtronic's Annual Report on Form 10-K for the year ended April 28, 2006. Actual results may differ materially from anticipated results.
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Publication:Business Wire
Article Type:Clinical report
Date:May 31, 2007
Words:580
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