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'Fat' gene not to blame for obesity: nearby bit of noncoding DNA real culprit, researchers say.
Researchers have discovered a "genetic switch" that determines whether people burn extra calories or save them as fat. A genetic variant tightly linked to obesity causes fat-precursor cells to become energy-storing white fat instead of energy-burning beige fat, researchers report online August 19 in the New England Journal of Medicine.
Scientists had thought that the variant alters a gene called FTO in the brain to increase appetite. The new work shows that FTO is not the cause of...
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